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MedKoo Cat#: 561556 | Name: DHBP
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DHBP, also known as Benzoresorcinol, is an activator of WalKR TCS. It works via targeting erWalK and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain.

Chemical Structure

DHBP
CAS#131-56-6

Theoretical Analysis

MedKoo Cat#: 561556

Name: DHBP

CAS#: 131-56-6

Chemical Formula: C13H10O3

Exact Mass: 214.0630

Molecular Weight: 214.22

Elemental Analysis: C, 72.89; H, 4.71; O, 22.41

Price and Availability

Size Price Availability Quantity
25g USD 250.00 2 weeks
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Related CAS #
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Synonym
DHBP; Benzoresorcinol;
IUPAC/Chemical Name
2,4-Dihydroxybenzophenone
InChi Key
ZXDDPOHVAMWLBH-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H10O3/c14-10-6-7-11(12(15)8-10)13(16)9-4-2-1-3-5-9/h1-8,14-15H
SMILES Code
O=C(C1=CC=CC=C1)C2=CC=C(O)C=C2O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 214.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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A new strategy for fabrication of water dispersible and biodegradable fluorescent organic nanoparticles with AIE and ESIPT characteristics and their utilization for bioimaging. Talanta. 2017 Nov 1;174:803-808. doi: 10.1016/j.talanta.2017.07.010. Epub 2017 Jul 1. PubMed PMID: 28738657. 4: Zhao H, Huo W, Li J, Ma X, Xia W, Pang Z, Xie M, Xu S, Cai Z. Exposure to benzophenones, parabens and triclosan among pregnant women in different trimesters. Sci Total Environ. 2017 Dec 31;607-608:578-585. doi: 10.1016/j.scitotenv.2017.07.003. Epub 2017 Jul 27. PubMed PMID: 28709092. 5: Chen F, Huber C, Schröder P. Fate of the sunscreen compound oxybenzone in Cyperus alternifolius based hydroponic culture: Uptake, biotransformation and phytotoxicity. Chemosphere. 2017 Sep;182:638-646. doi: 10.1016/j.chemosphere.2017.05.072. Epub 2017 May 12. PubMed PMID: 28527417. 6: Wu MH, Xie DG, Xu G, Sun R, Xia XY, Liu WL, Tang L. Benzophenone-type UV filters in surface waters: An assessment of profiles and ecological risks in Shanghai, China. Ecotoxicol Environ Saf. 2017 Jul;141:235-241. doi: 10.1016/j.ecoenv.2017.03.013. Epub 2017 Apr 6. PubMed PMID: 28359989. 7: Bu Y, Feng J, Wang X, Tian Y, Sun M, Luo C. In situ hydrothermal growth of polyaniline coating for in-tube solid-phase microextraction towards ultraviolet filters in environmental water samples. J Chromatogr A. 2017 Feb 3;1483:48-55. doi: 10.1016/j.chroma.2016.12.077. Epub 2016 Dec 29. PubMed PMID: 28063640. 8: Shin S, Go RE, Kim CW, Hwang KA, Nam KH, Choi KC. Effect of benzophenone-1 and octylphenol on the regulation of epithelial-mesenchymal transition via an estrogen receptor-dependent pathway in estrogen receptor expressing ovarian cancer cells. Food Chem Toxicol. 2016 Jul;93:58-65. doi: 10.1016/j.fct.2016.04.026. Epub 2016 May 1. PubMed PMID: 27145024. 9: Zhou W, Wang PG, Wittenberg JB, Rua D, Krynitsky AJ. Simultaneous determination of cosmetics ingredients in nail products by fast gas chromatography with tandem mass spectrometry. J Chromatogr A. 2016 May 13;1446:134-40. doi: 10.1016/j.chroma.2016.04.003. Epub 2016 Apr 2. PubMed PMID: 27083261. 10: Ji Q, Chen PJ, Qin G, Deng X, Hao Z, Wawrzak Z, Yeo WS, Quang JW, Cho H, Luo GZ, Weng X, You Q, Luan CH, Yang X, Bae T, Yu K, Jiang H, He C. Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus. Nat Commun. 2016 Mar 18;7:11000. doi: 10.1038/ncomms11000. Retraction in: Nat Commun. 2017 Feb 06;8:14331. PubMed PMID: 26987594; PubMed Central PMCID: PMC4802049. 11: Bae J, Kim S, Kannan K, Buck Louis GM. Couples' urinary concentrations of benzophenone-type ultraviolet filters and the secondary sex ratio. Sci Total Environ. 2016 Feb 1;543(Pt A):28-36. doi: 10.1016/j.scitotenv.2015.11.019. Epub 2015 Nov 12. PubMed PMID: 26575635; PubMed Central PMCID: PMC4688162. 12: Buck Louis GM, Chen Z, Kim S, Sapra KJ, Bae J, Kannan K. Urinary concentrations of benzophenone-type ultraviolet light filters and semen quality. Fertil Steril. 2015 Oct;104(4):989-996. doi: 10.1016/j.fertnstert.2015.07.1129. Epub 2015 Aug 5. PubMed PMID: 26253817; PubMed Central PMCID: PMC4592813. 13: Sun H, Li Y, Huang C, Peng J, Yang J, Sun X, Zang S, Chen J, Zhang X. Solid-phase extraction based on a molecularly imprinted polymer for the selective determination of four benzophenones in tap and river water. J Sep Sci. 2015 Oct;38(19):3412-20. doi: 10.1002/jssc.201500419. Epub 2015 Aug 26. PubMed PMID: 26179642. 14: Ma T, Li Z, Niu Q, Li Y, Zhou W. Double dispersant-assisted ionic liquid dispersive liquid-liquid microextraction coupled with capillary electrophoresis for the determination of benzophenone-type ultraviolet filters in sunscreen cosmetic product. Electrophoresis. 2015 Oct;36(20):2530-7. doi: 10.1002/elps.201500004. Epub 2015 Aug 19. PubMed PMID: 26105533. 15: Wang YC, Sun Y, Cui R, Li YL, Zhang BX. [Determination of 2,4-dihydroxybenzophenone in mouse brain by high performance liquid chromatography]. Beijing Da Xue Xue Bao. 2015 Jun 18;47(3):541-7. Chinese. PubMed PMID: 26080890. 16: Li J, Ma LY, Xu L, Shi ZG. A novel two-dimensional liquid-chromatography method for online prediction of the toxicity of transformation products of benzophenones after water chlorination. Anal Bioanal Chem. 2015 Aug;407(20):6137-48. doi: 10.1007/s00216-015-8789-9. Epub 2015 Jun 6. PubMed PMID: 26048057. 17: Pouliou FM, Thireou TN, Eliopoulos EE, Tsoungas PG, Labrou NE, Clonis YD. Isoenzyme- and allozyme-specific inhibitors: 2,2'-dihydroxybenzophenones and their carbonyl N-analogues that discriminate between human glutathione transferase A1-1 and P1-1 allozymes. Chem Biol Drug Des. 2015 Nov;86(5):1055-63. doi: 10.1111/cbdd.12574. Epub 2015 May 14. PubMed PMID: 25891019. 18: In SJ, Kim SH, Go RE, Hwang KA, Choi KC. Benzophenone-1 and nonylphenol stimulated MCF-7 breast cancer growth by regulating cell cycle and metastasis-related genes via an estrogen receptor α-dependent pathway. J Toxicol Environ Health A. 2015;78(8):492-505. doi: 10.1080/15287394.2015.1010464. PubMed PMID: 25849766. 19: Li J, Xu L, Xue S, Xu L. [Determination of ultraviolet filters in environmental aqueous samples by dispersive liquid-liquid microextraction with online derivatization-gas chromatography-mass spectrometry]. Se Pu. 2014 Oct;32(10):1138-43. Chinese. PubMed PMID: 25739276. 20: Kim SH, Hwang KA, Shim SM, Choi KC. Growth and migration of LNCaP prostate cancer cells are promoted by triclosan and benzophenone-1 via an androgen receptor signaling pathway. Environ Toxicol Pharmacol. 2015 Mar;39(2):568-76. doi: 10.1016/j.etap.2015.01.003. Epub 2015 Jan 20. PubMed PMID: 25682003.