MedKoo Cat#: 571362 | Name: M1000907

Description:

WARNING: This product is for research use only, not for human or veterinary use.

M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms. Increased 5-HT2A receptor activity in certain brain regions may contribute to repetitive behaviors, so treatment with a selective 5-HT2A receptor antagonist has been proposed to improve cognitive flexibility in individuals with ASD.

Chemical Structure

M1000907
M1000907
CAS#880759-45-5

Theoretical Analysis

MedKoo Cat#: 571362

Name: M1000907

CAS#: 880759-45-5

Chemical Formula: C22H28FNO3

Exact Mass: 373.2053

Molecular Weight: 373.47

Elemental Analysis: C, 70.75; H, 7.56; F, 5.09; N, 3.75; O, 12.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
M1000907; M-1000907; M 1000907
IUPAC/Chemical Name
α-(3,4-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidine methanol
InChi Key
XDKPDXLUSMCEDG-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28FNO3/c1-26-20-8-5-18(15-21(20)27-2)22(25)17-10-13-24(14-11-17)12-9-16-3-6-19(23)7-4-16/h3-8,15,17,22,25H,9-14H2,1-2H3
SMILES Code
OC(C1=CC=C(OC)C(OC)=C1)C2CCN(CCC3=CC=C(F)C=C3)CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 373.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lacivita E, Perrone R, Margari L, Leopoldo M. Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions. J Med Chem. 2017 Oct 30. doi: 10.1021/acs.jmedchem.7b00965. [Epub ahead of print] PubMed PMID: 29039668.