MedKoo Cat#: 530944 | Name: TAN-420C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TAN-420C, also known as Dihydroherbimycin C, is an antibiotic. TAN 420C is a minor analogue of the herbimycin complex, isolated from Streptomyces hygroscopicus. TAN 420C is known to exhibit antitumour activity.

Chemical Structure

TAN-420C
TAN-420C
CAS#91700-91-3

Theoretical Analysis

MedKoo Cat#: 530944

Name: TAN-420C

CAS#: 91700-91-3

Chemical Formula: C29H42N2O9

Exact Mass: 562.2890

Molecular Weight: 562.66

Elemental Analysis: C, 61.91; H, 7.52; N, 4.98; O, 25.59

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Synonym
TAN-420C; TAN 420C; TAN420C; Antibiotic TAN 420C; Dihydroherbimycin C; dihydro-herbimycin B
IUPAC/Chemical Name
(4E,6E,8S,9S,10E,12S,13R,14S,16S,17R)-12,15,13-trihydroxy-8,14,17-trimethoxy-4,10,12,16-tetramethyl-3-oxo-2-aza-1(1,3)-benzenacycloheptadecaphane-4,6,10-trien-9-yl carbamate
InChi Key
QCXSABHHRSWSID-FXBOSWKYSA-N
InChi Code
InChI=1S/C29H42N2O9/c1-15-9-8-10-22(37-5)27(40-29(30)36)17(3)11-16(2)24(33)23(38-6)12-18(4)26(39-7)20-13-19(32)14-21(25(20)34)31-28(15)35/h8-11,13-14,16,18,22-24,26-27,32-34H,12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8+,15-9+,17-11+/t16-,18-,22-,23-,24+,26+,27-/m0/s1
SMILES Code
OC1=CC(N2)=C(O)C([C@H](OC)[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C/C=C(C)/C2=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 562.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lin, L.-Z.,Blaskó, G., and Cordell, G.A. H-NMR analysis of herbimycins and dihydro-herbimycins. J. Nat. Prod. 51(6), 1161-1165 (1988). 2. Tanida, S.,Muroi, M., and Hasegawa, T. Antibiotic tan-420, its production and use. EP0110710 A2, (1990).