Temefos | CAS# 3383-96-8 | Insecticide

MedKoo Cat#: 571328 | Name: Temefos

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Temefos is an organothiophosphate insecticide.

Chemical Structure

Temefos

CAS#3383-96-8

Theoretical Analysis

MedKoo Cat#: 571328

Name: Temefos

CAS#: 3383-96-8

Chemical Formula: C16H20O6P2S3

Exact Mass: 465.9897

Molecular Weight: 466.46

Elemental Analysis: C, 41.20; H, 4.32; O, 20.58; P, 13.28; S, 20.62

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 235.00

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Related CAS #

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Synonym

Temefos; Abate; Bithion; Lyphor; Procida

IUPAC/Chemical Name

Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl este

InChi Key

WWJZWCUNLNYYAU-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3

SMILES Code

S=P(OC)(OC)OC1=CC=C(SC2=CC=C(OP(OC)(OC)=S)C=C2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 466.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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PMID: 39206467. 4: Alvarado-Castro VM, Vargas-De-León C, Paredes-Solis S, Li-Martin A, Nava- Aguilera E, Morales-Pérez A, Legorreta-Soberanis J, Sánchez-Gervacio BM, Cockcroft A, Andersson N. The influence of gender and temephos exposure on community participation in dengue prevention: a compartmental mathematical model. BMC Infect Dis. 2024 May 2;24(1):463. doi: 10.1186/s12879-024-09341-w. PMID: 38698345; PMCID: PMC11067291. 5: Piedra LA, Martinez Y, Camacho E, Garcia I, Rodriguez D, Vanlerberghe V, Marquetti MDC. Temephos Resistance Status of Aedes aegypti Populations From Havana, Cuba. J Am Mosq Control Assoc. 2024 Jun 1;40(2):117-120. doi: 10.2987/23-7164. PMID: 38666434. 6: Bu X, Wang M, Yuan J, Song J, Luan G, Yu J, Wang Y, Li Y, Wang C, Zhang L. SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps. J Immunol Res. 2024 Mar 21;2024:8553447. doi: 10.1155/2024/8553447. PMID: 38550710; PMCID: PMC10978078. 7: Poulton BC, Colman F, Anthousi A, Sattelle DB, Lycett GJ. Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito. PLoS Negl Trop Dis. 2024 Feb 20;18(2):e0011595. doi: 10.1371/journal.pntd.0011595. PMID: 38377131; PMCID: PMC10906864. 8: Da-Silva OF, Adelowo AR, Babalola AA, Ikeji CN, Owoeye O, Rocha JBT, Adedara IA, Farombi EO. Diphenyl Diselenide Through Reduction of Inflammation, Oxidative Injury and Caspase-3 Activation Abates Doxorubicin-Induced Neurotoxicity in Rats. Neurochem Res. 2024 Apr;49(4):1076-1092. doi: 10.1007/s11064-023-04098-1. Epub 2024 Jan 24. PMID: 38267690. 9: He X, Ma M, Ma X. [Surveillance on dengue vector Aedes albopictus in Ningbo City in 2021]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2023 Sep 27;35(4):379-382. Chinese. doi: 10.16250/j.32.1374.2023050. PMID: 37926473. 10: Prasad P, Lata S, Kumar D, Gupta SK, Saxena R, Arya DK, Singh H. Susceptibility status of Aedes aegypti (Diptera: Culicidae) against insecticides of public health use in Delhi and NCR region, India. J Vector Borne Dis. 2023 Jul-Sep;60(3):300-306. doi: 10.4103/0972-9062.374044. PMID: 37843241. 11: Wan-Norafikah O, Aliah-Diyanah S, Atiqah-Izzah Z, Chen CD, Sofian-Azirun M, Lailatul-Nadhirah A, Ibahim MJ. Assessing the bioefficacy of a commercial temephos formulation (Temebate®) for controlling Aedes albopictus larvae in different land use localities in Malaysia. Exp Parasitol. 2023 Nov;254:108627. doi: 10.1016/j.exppara.2023.108627. Epub 2023 Oct 5. PMID: 37802180. 12: Aldridge RL, Alto BW, Roxanne Connelly C, Okech B, Siegfried B, Eastmond BH, Alomar AA, Linthicum KJ. Does prior exposure to larvicides influence dengue virus susceptibility in Aedes aegypti (Diptera: Culicidae)? J Med Entomol. 2024 Jan 12;61(1):166-174. doi: 10.1093/jme/tjad137. PMID: 37788073. 13: Shettima A, Ishak IH, Lau B, Abu Hasan H, Miswan N, Othman N. Quantitative proteomics analysis of permethrin and temephos-resistant Ae. aegypti revealed diverse differentially expressed proteins associated with insecticide resistance from Penang Island, Malaysia. PLoS Negl Trop Dis. 2023 Sep 18;17(9):e0011604. doi: 10.1371/journal.pntd.0011604. PMID: 37721966; PMCID: PMC10538732. 14: Maestre-Serrano R, Flórez-Rivadeneira Z, Castro-Camacho JM, Ochoa-Bohórquez L, Gómez-Camargo D, Pareja-Loaiza P, Ponce-García G, Flores AE. Evaluation of susceptibility to organophosphates in populations of Aedes aegypti in La Guajira, Colombia. Biomedica. 2023 Jun 30;43(2):296-304. English, Spanish. doi: 10.7705/biomedica.6677. PMID: 37433166; PMCID: PMC10549234. 15: Sivabalakrishnan K, Thanihaichelvan M, Tharsan A, Eswaramohan T, Ravirajan P, Hemphill A, Ramasamy R, Surendran SN. Resistance to the larvicide temephos and altered egg and larval surfaces characterize salinity-tolerant Aedes aegypti. Sci Rep. 2023 May 19;13(1):8160. doi: 10.1038/s41598-023-35128-1. PMID: 37208485; PMCID: PMC10198600. 16: Ramzan H, Manzoor F, Oneeb M. Current status of insecticide resistance and its underlying mechanisms in Aedes aegypti (L.) in Punjab, Pakistan. J Vector Borne Dis. 2023 Jan-Mar;60(1):57-64. doi: 10.4103/0972-9062.353250. PMID: 37026220. 17: Hekal MH, Ali YM, Abdel-Haleem DR, Abu El-Azm FSM. Diversity oriented synthesis and SAR studies of new quinazolinones and related compounds as insecticidal agents against Culex pipiens L. Larvae and associated predator. Bioorg Chem. 2023 Apr;133:106436. doi: 10.1016/j.bioorg.2023.106436. Epub 2023 Feb 21. PMID: 36841047. 18: Piedra LA, Rodriguez MM, Lopez I, Ruiz A, Martinez LC, Garcia I, Rey J, Bisset JA. Insecticide Resistance Status of Aedes albopictus (Diptera: Culicidae) Populations from Cuba. J Med Entomol. 2023 May 12;60(3):487-493. doi: 10.1093/jme/tjac189. PMID: 36791252. 19: Teshome A, Erko B, Golassa L, Yohannes G, Irish SR, Zohdy S, Dugassa S. Laboratory-based efficacy evaluation of Bacillus thuringiensis var. israelensis and temephos larvicides against larvae of Anopheles stephensi in ethiopia. Malar J. 2023 Feb 9;22(1):48. doi: 10.1186/s12936-023-04475-9. Erratum in: Malar J. 2023 Oct 17;22(1):312. doi: 10.1186/s12936-023-04730-z. PMID: 36759908; PMCID: PMC9912598. 20: Moungthipmalai T, Puwanard C, Aungtikun J, Sittichok S, Soonwera M. Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators. Sci Rep. 2023 Feb 6;13(1):2119. doi: 10.1038/s41598-023-29421-2. PMID: 36746998; PMCID: PMC9902397.