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MedKoo Cat#: 571272 | Name: Thiodicarb

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thiodicarb is an insecticide.

Chemical Structure

Thiodicarb
Thiodicarb
CAS#59669-26-0

Theoretical Analysis

MedKoo Cat#: 571272

Name: Thiodicarb

CAS#: 59669-26-0

Chemical Formula: C10H14N4O6S3

Exact Mass: 382.0075

Molecular Weight: 382.42

Elemental Analysis: C, 31.41; H, 3.69; N, 14.65; O, 25.10; S, 25.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Thiodicarb; A93-29311; Nivral; Semevin; Lepricon
IUPAC/Chemical Name
Dimethyl N,N'-(thiobis((methylimino)carbonyloxy))bis(thioimidoacetate)
InChi Key
GUFFDERCUGUANO-OXAWKVHCSA-N
InChi Code
InChI=1S/C10H14N4O6S3/c1-13(9(15)19-11-7(5-21)17-3)23-14(2)10(16)20-12-8(6-22)18-4/h5-6H,1-4H3/b11-7-,12-8-
SMILES Code
O=C(O/N=C(OC)/C=S)N(SN(C(O/N=C(OC)/C=S)=O)C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 382.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bisht S, Chauhan R, Kumari B, Singh R. Fate of thiodicarb and its metabolite methomyl in sandy loam soil under laboratory conditions. Environ Monit Assess. 2015 Jul;187(7):429. doi: 10.1007/s10661-015-4640-1. Epub 2015 Jun 13. PubMed PMID: 26070994. 2: Moccelini SK, Vieira IC, de Lima F, Lucca BG, Barbosa AM, Ferreira VS. Determination of thiodicarb using a biosensor based on alfalfa sprout peroxidase immobilized in self-assembled monolayers. Talanta. 2010 Jun 30;82(1):164-70. doi: 10.1016/j.talanta.2010.04.015. Epub 2010 May 4. PubMed PMID: 20685452. 3: Dias E, Gomes M, Domingues C, Ramalheira E, Morais S, Pereira Mde L. Subacute effects of the thiodicarb pesticide on target organs of male Wistar rats: biochemical, histological, and flow cytometry studies. J Toxicol Environ Health A. 2013;76(9):533-9. doi: 10.1080/15287394.2013.785216. PubMed PMID: 23750999. 4: Ammon HL, Seymour RJ, Huffman WM, D'Silva TD. Thiodicarb. Acta Crystallogr C. 1995 Aug 15;51 ( Pt 8):1619-21. PubMed PMID: 8527099. 5: Satpal, Jain SK, Punia JS. Studies on biochemical changes in subacute thiodicarb toxicity in rats. Toxicol Int. 2010 Jan;17(1):30-2. doi: 10.4103/0971-6580.68347. PubMed PMID: 21042471; PubMed Central PMCID: PMC2964739. 6: Karunaratne KM, Plapp FW Jr. Biochemistry and genetics of thiodicarb resistance in the house fly (Diptera: Muscidae). J Econ Entomol. 1993 Apr;86(2):258-64. PubMed PMID: 8473601. 7: Lanning CL, Ayad HM, Abou-Donia MB. P-glycoprotein involvement in cuticular penetration of [14C]thiodicarb in resistant tobacco budworms. Toxicol Lett. 1996 Jun;85(3):127-33. PubMed PMID: 8644124. 8: Xu G, Li D. [Determination of thiodicarb by reversed-phase high performance liquid chromatography]. Se Pu. 1997 Nov;15(6):550-2. Chinese. PubMed PMID: 15739350. 9: Hoizey G, Canas F, Binet L, Kaltenbach ML, Jeunehomme G, Bernard MH, Lamiable D. Thiodicarb and methomyl tissue distribution in a fatal multiple compounds poisoning. J Forensic Sci. 2008 Mar;53(2):499-502. doi: 10.1111/j.1556-4029.2008.00676.x. PubMed PMID: 18366586. 10: Gunning RV, Moores GD, Devonshire AL. Insensitive Acetylcholinesterase and Resistance to Thiodicarb in Australian Helicoverpa armigera Hübner (Lepidoptera: Noctuidae). Pestic Biochem Physiol. 1996 May;55(1):21-8. PubMed PMID: 8980026. 11: Ware GW, Estesen BJ, Buck NA. Dislodgable insecticide residues on cotton foliage: acephate, AC 222,705, EPN, fenvalerate, methomyl, methyl parathion, permethrin, and thiodicarb. Bull Environ Contam Toxicol. 1980 Oct;25(4):608-15. PubMed PMID: 7437564. 12: Yi MQ, Liu HX, Shi XY, Liang P, Gao XW. Inhibitory effects of four carbamate insecticides on acetylcholinesterase of male and female Carassius auratus in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):113-6. Epub 2006 Feb 3. PubMed PMID: 16461013. 13: Rahman MM, Abd El-Aty AM, Kim SW, Lee YJ, Na TW, Park JS, Shin HC, Shim JH. Simultaneous determination and identity confirmation of thiodicarb and its degradation product methomyl in animal-derived foodstuffs using high-performance liquid chromatography with fluorescence detection and tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:97-104. doi: 10.1016/j.jchromb.2016.12.013. Epub 2016 Dec 9. PubMed PMID: 27978474. 14: Catalá-Icardo M, Meseguer-Lloret S, Torres-Cartas S. Photoinduced chemiluminescence determination of carbamate pesticides. Photochem Photobiol Sci. 2016 May 11;15(5):626-34. doi: 10.1039/c6pp00056h. Epub 2016 Apr 15. PubMed PMID: 27079156. 15: Huertas Pérez JF, Sejerøe-Olsen B, Fernández Alba AR, Schimmel H, Dabrio M. Accurate determination of selected pesticides in soya beans by liquid chromatography coupled to isotope dilution mass spectrometry. Talanta. 2015 May;137:120-9. doi: 10.1016/j.talanta.2015.01.020. Epub 2015 Jan 29. PubMed PMID: 25770614. 16: Wheeler TA, Lawrence KS, Porter DO, Keeling W, Mullinix BG Jr. The relationship between environmental variables and response of cotton to nematicides. J Nematol. 2013 Mar;45(1):8-16. PubMed PMID: 23589654; PubMed Central PMCID: PMC3625136. 17: Tong H, Su Q, Zhou X, Bai L. Field resistance of Spodoptera litura (Lepidoptera: Noctuidae) to organophosphates, pyrethroids, carbamates and four newer chemistry insecticides in Hunan, China. J Pest Sci (2004). 2013;86:599-609. Epub 2013 May 7. PubMed PMID: 23970847; PubMed Central PMCID: PMC3745612. 18: Lu YH, He YP, Gao XW. Comparative studies on acetylcholinesterase characteristics between the aphids, Sitobion avenae and Rhopalosiphum padi. J Insect Sci. 2013;13:9. doi: 10.1673/031.013.0901. PubMed PMID: 23879406; PubMed Central PMCID: PMC3735166. 19: Brickle DS, Turnipseed SG, Sullivan MJ. Efficacy of insecticides of different chemistries against Helicoverpa zea (Lepidoptera: Noctuidae) in transgenic Bacillus thuringiensis and conventional cotton. J Econ Entomol. 2001 Feb;94(1):86-92. PubMed PMID: 11233138. 20: Lanning CL, Fine RL, Corcoran JJ, Ayad HM, Rose RL, Abou-Donia MB. Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance. Biochim Biophys Acta. 1996 Oct 24;1291(2):155-62. PubMed PMID: 8898877.