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MedKoo Cat#: 571248 | Name: Septamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Septamycin is a polycyclic, polyether, monocarboxylic acid antibiotic isolated from strain of Streptomyces albus. antibiotic.

Chemical Structure

Septamycin
CAS#54927-63-8

Theoretical Analysis

MedKoo Cat#: 571248

Name: Septamycin

CAS#: 54927-63-8

Chemical Formula: C48H82O16

Exact Mass: 914.5603

Molecular Weight: 915.17

Elemental Analysis: C, 63.00; H, 9.03; O, 27.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Septamycin; A28695A; A 28695A; A-28695A
IUPAC/Chemical Name
(2R)-2-((2S,3R,4S,5S,6S)-2-hydroxy-6-(((2R,3R,4R,5S,7S,9R,10R)-2-((2S,2'R,5'R)-5'-((3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)octahydro-[2,2'-bifuran]-5-yl)-3,9-dimethoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)methyl)-4-methoxy-5-(((2S,5S,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5-dimethyltetrahydro-2H-pyran-2-yl)propanoic acid
InChi Key
QZVSDERYSHAHPU-LFEMCTADSA-N
InChi Code
InChI=1S/C48H82O16/c1-24-21-25(2)46(10,51)63-40(24)35-16-15-33(58-35)34-17-19-37(59-34)45(9)42(56-14)28(5)48(64-45)26(3)36(54-12)22-31(60-48)23-38-44(8,62-39-20-18-32(53-11)30(7)57-39)41(55-13)27(4)47(52,61-38)29(6)43(49)50/h24-42,51-52H,15-23H2,1-14H3,(H,49,50)/t24-,25+,26+,27+,28+,29-,30+,31-,32-,33+,34-,35+,36+,37?,38-,39-,40?,41-,42+,44-,45+,46-,47-,48-/m0/s1
SMILES Code
C[C@@H]1[C@@H](OC)[C@](C2O[C@H]([C@@H]3O[C@@H](C4[C@@H](C)C[C@@H](C)[C@@](C)(O)O4)CC3)CC2)(C)O[C@]1([C@H](C)[C@H](OC)C5)O[C@@H]5C[C@H]6[C@@](O[C@H]7CC[C@H](OC)[C@@H](C)O7)(C)[C@@H](OC)[C@@H](C)[C@]([C@@H](C)C(O)=O)(O)O6
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 915.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rodios NA, Anteunis MJ. Solution conformation of septamycin and its sodium salt. J Antibiot (Tokyo). 1978 Apr;31(4):294-301. PubMed PMID: 659327. 2: Keller-Juslén C, King HD, Kis ZL, von Wartburg A. Septamycin, a polyether antibiotic. Taxonomy, fermentation, isolation and characterization. J Antibiot (Tokyo). 1975 Nov;28(11):854-9. PubMed PMID: 172482. 3: Meingassner JG, Hildebrandt J, Leskova R, Mieth H. Laboratory studies on the anticoccidial activity of septamycin. Poult Sci. 1977 Jul;56(4):1281-8. PubMed PMID: 605085. 4: Ricketts AP, Dirlam JP, Shively JE. Anticoccidial efficacy and chicken toleration of potent new polyether ionophores. 1. The septamycin relative CP-82,009. Poult Sci. 1992 Oct;71(10):1626-30. PubMed PMID: 1454680. 5: Siegel MM, McGahren WJ, Tomer KB, Chang TT. Applications of fast atom bombardment mass spectrometry and fast atom bombardment mass spectrometry-mass spectrometry to the maduramicins and other polyether antibiotics. Biomed Environ Mass Spectrom. 1987 Jan;14(1):29-38. PubMed PMID: 2952192. 6: Dirlam JP, Belton AM, Bordner J, Cullen WP, Huang LH, Kojima Y, Maeda H, Nishiyama S, Oscarson JR, Ricketts AP, et al. CP-82,009, a potent polyether anticoccidial related to septamycin and produced by Actinomadura sp. J Antibiot (Tokyo). 1992 Mar;45(3):331-40. PubMed PMID: 1577662.