Synonym
Buthalital sodium; baytinal
IUPAC/Chemical Name
Barbituric acid, 5-allyl-5-isobutyl-2-thio-, sodium salt
InChi Key
CNMSPFHQEFCNST-UHFFFAOYSA-L
InChi Code
InChI=1S/C11H16N2O2S.2Na/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15;;/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16);;/q;2*+1/p-2
SMILES Code
S=C([N-]C(C1(CC=C)CC(C)C)=O)[N-]C1=O.[Na+].[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
284.28
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Buthalital sodium; baytinal; 1: IVANOV I, ANGELOV A, VASILEV Z, RAKILOVSKA I. [ATTEMPTED CONTROL OF BLOOD LOSS AND COMPLICATIONS IN LEGAL ABORTION UNDER TOTAL BAYTINAL ANESTHESIA USING INTRAVENOUS METHYLERGOMETRINE]. Akush Ginekol (Sofiia). 1964;3:81-4. Bulgarian. PubMed PMID: 14244651.
2: BOJADZIEV S. [BAYTINAL IN TABUN POISONING]. Folia Med (Plovdiv). 1964;6:269-73. German. PubMed PMID: 14297587.
3: POLITOWSKI M. [Baytinal, a new narcotic]. Pol Przegl Chir. 1958 Jun;30(6):685-9. PubMed PMID: 13601185.
4: TRUMP K. [Baytinal, an ultrashort-lasting narcotic]. Med Klin. 1957 Apr 12;52(15):593-4. German. PubMed PMID: 13430302.
5: WESTERBORN A, STENBERG K. [Ultrashort anesthesia with baytinal]. Nord Med. 1955 Oct 20;54(42):1589-92. Swedish. PubMed PMID: 13280122.
6: RIEBEL O, TABORSKA D. [Personal experiences with short-acting anesthetic baytinal]. Cesk Oftalmol. 1957 Sep;13(5):388-90. Czech. PubMed PMID: 13489799.
7: PROMMERSBERGER S. [Baytinal anesthesia in geriatric surgery]. Chirurg. 1959 Dec;30:552-5. German. PubMed PMID: 14435055.
8: HARCKEN W Jr. [Experiences with the ultra short narcotic baytinal with reference to its use in general practice]. Ther Ggw. 1955 Nov;94(11):401-3. German. PubMed PMID: 13299252.
9: SCHILDT BE, SCHILDT EE. Thialisobumal (Baytinal) as an intravenous anaesthetic for rabbits. Acta Pharmacol Toxicol (Copenh). 1962;19:377-88. PubMed PMID: 13991690.
10: CENTNER F. [Experience with baytinal, an anesthetic with ultra-short action]. Zentralbl Chir. 1956 Jun 9;81(23):938-40. German. PubMed PMID: 13353578.
11: MAYRHOFER O, REMES I. [Baytinal for short-term intravenous anesthesia; preliminary report]. Wien Klin Wochenschr. 1956 Feb 10;68(6):103-4. German. PubMed PMID: 13312274.
12: RIESZ E, CSASZAR G. [On the use of Baytinal in stretching of joint contractures]. Z Rheumaforsch. 1961 Dec;20:436-40. German. PubMed PMID: 14492202.
13: KJURCIEV K, LAZAROV A, LAZAREVSKI M. ["BAYTINAL"--AN ANESTHETIC OF ULTRASHORT DURATION IN ARTIFICIAL ABORTION]. Lijec Vjesn. 1963 Oct;85:1155-8. Undetermined Language. PubMed PMID: 14097620.
14: KOCH L. [Ultra-short narcosis with baytinal for short surgical interventions]. Ther Ggw. 1957 Oct;96(10):365-7. German. PubMed PMID: 13496018.
15: SABA GM. [Tests of ultra-short-action thiobarbituric baytinal in urological diagnosis]. Minerva Anestesiol. 1956 Nov;22(11):379-81. Italian. PubMed PMID: 13387010.
16: FREUCHEN IP. [Baytinal, 5-allyl-5-(2-methylpropyl)-thiobarbituric acid, a new barbiturate with ultra-short action]. Ugeskr Laeger. 1956 Sep 13;118(37):1065-8. Danish. PubMed PMID: 13392076.
17: KRUMPMANN FJ. [Report on 1500 baytinal narcoses in gynecological dispensaries]. Munch Med Wochenschr. 1955 Dec 30;97(52):1744. German. PubMed PMID: 13288531.
18: SMULA Z, MINAR J. [Baytinal, an anesthetic of ultrashort duration for ambulatory surgery]. Cas Lek Cesk. 1957 Nov 29;96(48):172-5. Czech. PubMed PMID: 13500372.
19: GIEBEL G. [Experiences with ultrashort-acting anesthetic, baytinal, in gynecology and obstetrics]. Anaesthesist. 1955 Jun;4(3):71-2. German. PubMed PMID: 13238806.
20: KUNZ T. [Ultra-short anesthesia with baytinal in ambulant surgery]. Med Klin. 1954 Oct 22;49(43):1727-9. German. PubMed PMID: 13223366.