A 85 4777 | CAS# 117009-82-2 | Antiinflammatory agent

MedKoo Cat#: 571207 | Name: A 85 4777

Description:

WARNING: This product is for research use only, not for human or veterinary use.

A 85 4777 is an antiinflammatory agent with nonclassical immunosuppressive properties. It is a homoperazine derivative.

Chemical Structure

A 85 4777

CAS#117009-82-2

Theoretical Analysis

MedKoo Cat#: 571207

Name: A 85 4777

CAS#: 117009-82-2

Chemical Formula: C20H32N2O2

Exact Mass: 332.2464

Molecular Weight: 332.49

Elemental Analysis: C, 72.25; H, 9.70; N, 8.43; O, 9.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

A 85 4777; A 8547777; A85-4777

IUPAC/Chemical Name

1H-1,4-Diazepine, 1-(3,5-bis(1,1-dimethylethyl)-4-hydroxybenzoyl)hexahydro-

InChi Key

LYRRSBJFMOFHBF-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H32N2O2/c1-19(2,3)15-12-14(13-16(17(15)23)20(4,5)6)18(24)22-10-7-8-21-9-11-22/h12-13,21,23H,7-11H2,1-6H3

SMILES Code

O=C(N1CCNCCC1)C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 332.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Bartlett RR, Schleyerbach R, Schorlemmer KU, Wolf E. Pharmacological profile of A85 4777, a novel antiinflammatory agent with nonclassical immunosuppressive properties. Transplant Proc. 1990 Aug;22(4):1666-70. PubMed PMID: 2389430. 2: Schorlemmer H, Bartlett RR, Wolf E, Seiler FR. Prolongation of allogeneic transplanted skin grafts by A85 4777, a new immunosuppressive homopiperazine derivative. Transplant Proc. 1990 Aug;22(4):1671-3. PubMed PMID: 2389431. 3: Eisenmann D, Knipp H, Laube H, Stegmann T. Prevention of cytomegalovirus disease in heart transplant recipients by prophylaxis with cytomegalovirus hyperimmune globulin plus oral acyclovir. Transplant Proc. 1990 Oct;22(5):2322-3. PubMed PMID: 2171169.