Ianthelliformisamine C TFA | CAS#1643593-30-9 | antibiotic enhancer

MedKoo Cat#: 561372 | Name: Ianthelliformisamine C TFA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ianthelliformisamine C TFA is an antibiotic enhancer against resistant Gram-negative bacteria.

Chemical Structure

Ianthelliformisamine C TFA

CAS#1643593-30-9

Theoretical Analysis

MedKoo Cat#: 561372

Name: Ianthelliformisamine C TFA

CAS#: 1643593-30-9

Chemical Formula: C34H40Br4F6N4O8

Exact Mass:

Molecular Weight: 1066.32

Elemental Analysis: C, 38.30; H, 3.78; Br, 29.97; F, 10.69; N, 5.25; O, 12.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Ianthelliformisamine C TFA; Ianthelliformisamine-C TFA; IanthelliformisamineC TFA; Ianthelliformisamine C TFA salt;

IUPAC/Chemical Name

(2E,2'E)-N,N'-((butane-1,4-diylbis(azanediyl))bis(propane-3,1-diyl))bis(3-(3,5-dibromo-4-methoxyphenyl)acrylamide) bis(2,2,2-trifluoroacetate)

InChi Key

ITGKGTPPRJVLIB-QZKABRJGSA-N

InChi Code

InChI=1S/C30H38Br4N4O4.2C2HF3O2/c1-41-29-23(31)17-21(18-24(29)32)7-9-27(39)37-15-5-13-35-11-3-4-12-36-14-6-16-38-28(40)10-8-22-19-25(33)30(42-2)26(34)20-22;2*3-2(4,5)1(6)7/h7-10,17-20,35-36H,3-6,11-16H2,1-2H3,(H,37,39)(H,38,40);2*(H,6,7)/b9-7+,10-8+;;

SMILES Code

O=C(NCCCNCCCCNCCCNC(/C=C/C1=CC(Br)=C(OC)C(Br)=C1)=O)/C=C/C2=CC(Br)=C(OC)C(Br)=C2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,066.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pieri C, Borselli D, Di Giorgio C, De Méo M, Bolla JM, Vidal N, Combes S, Brunel JM. New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria. J Med Chem. 2014 May 22;57(10):4263-72. doi: 10.1021/jm500194e. Epub 2014 May 13. PubMed PMID: 24801877. 2: Khan FA, Ahmad S, Kodipelli N, Shivange G, Anindya R. Syntheses of a library of molecules on the marine natural product ianthelliformisamines platform and their biological evaluation. Org Biomol Chem. 2014 Jun 21;12(23):3847-65. doi: 10.1039/c3ob42537a. PubMed PMID: 24668192. 3: Xu M, Davis RA, Feng Y, Sykes ML, Shelper T, Avery VM, Camp D, Quinn RJ. Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. J Nat Prod. 2012 May 25;75(5):1001-5. doi: 10.1021/np300147d. Epub 2012 Apr 19. PubMed PMID: 22515429.