MedKoo Cat#: 571197 | Name: Trichlormethine HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Trichlormethine is a chemical irritant that causes genetic effects with human therapeutic dosage. It interferes with sperm heads through action on spermatocytes. It influences the body weight, reduces the relative weight of the testes, damages spermatogenesis in the seminiferous tubules (spermatids), causes appearance of multinucleate cells in the epididymides, and increases rate of abnormality of the heads of fully mature spermatozoa.

Chemical Structure

Trichlormethine HCl
Trichlormethine HCl
CAS#817-09-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 571197

Name: Trichlormethine HCl

CAS#: 817-09-4 (HCl)

Chemical Formula: C6H13Cl4N

Exact Mass: 203.0035

Molecular Weight: 240.98

Elemental Analysis: C, 29.91; H, 5.44; Cl, 58.84; N, 5.81

Price and Availability

Size Price Availability Quantity
100mg USD 90.00 Ready to ship
200mg USD 150.00 Ready to ship
500mg USD 300.00 Ready to ship
1g USD 450.00 Ready to ship
2g USD 750.00 Ready to ship
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Related CAS #
817-09-4 (HCl) 555-77-1 (free base)
Synonym
Trichlormethine; NSC 30211; NSC-30211; NSC30211; Trichlormethine HCl; trimustine hydrochloride;
IUPAC/Chemical Name
2-Chloro-N,N-bis(2-chloroethyl)ethanamine hydrochloride
InChi Key
VEAUDLLZYJVHRI-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H12Cl3N.ClH/c7-1-4-10(5-2-8)6-3-9;/h1-6H2;1H
SMILES Code
ClCCN(CCCl)CCCl.[H]Cl
Appearance
White to off-white, solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 240.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Trichlormethine (trimustine hydrochloride). IARC Monogr Eval Carcinog Risks Hum. 1990;50:143-9. Review. PubMed PMID: 2292796. 2: Sýkora I, Gandalovicová D. Trichlormethine hydrochloride and correlation of its mutagenic and toxic effects on male germ cells in mice. Mutat Res. 1992 Apr; 266(2):291-7. PubMed PMID: 1373838. 3: Koza I, Bohunický L, Svancárová L, Mardiak J, Gyárfás J, Cerný V. Treatment of advanced Hodgkin's disease with modified MOPP regimens. A long-term observation. Neoplasma. 1989;36(6):709-18. PubMed PMID: 2615874.