A 60586 | CAS# 146667-75-6 | Ergosterol Biosynthesis Inhibitor

MedKoo Cat#: 571172 | Name: A 60586

Description:

WARNING: This product is for research use only, not for human or veterinary use.

A 60586 is a non-azole inhibitor of ergosterol biosynthesis. A60586 displays in-vitro antifungal activity and inhibits lanosterol 14alpha-demethylase.

Chemical Structure

A 60586

CAS#146667-75-6

Theoretical Analysis

MedKoo Cat#: 571172

Name: A 60586

CAS#: 146667-75-6

Chemical Formula: C26H29NO

Exact Mass: 371.2249

Molecular Weight: 371.52

Elemental Analysis: C, 84.06; H, 7.87; N, 3.77; O, 4.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

A 60586; A-60586; A60586

IUPAC/Chemical Name

2-Naphthalenol, 5-(((2-(1,1'-biphenyl)-4-ylethyl)methylamino)methyl)-5,6,7,8-tetrahydro-

InChi Key

UTBRFUHMQQIVFL-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H29NO/c1-27(19-24-9-5-8-23-18-25(28)14-15-26(23)24)17-16-20-10-12-22(13-11-20)21-6-3-2-4-7-21/h2-4,6-7,10-15,18,24,28H,5,8-9,16-17,19H2,1H3

SMILES Code

OC1=CC=C2C(CN(CCC3=CC=C(C4=CC=CC=C4)C=C3)C)CCCC2=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 371.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Capobianco JO, Doran CC, Goldman RC, De B. A non-azole inhibitor of lanosterol 14 alpha-methyl demethylase in Candida albicans. J Antimicrob Chemother. 1992 Dec;30(6):781-90. PubMed PMID: 1289352.