MedKoo Cat#: 571136 | Name: Furalaxyl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Furalaxyl is an acylamino chiral fungicide.

Chemical Structure

Furalaxyl
Furalaxyl
CAS#57646-30-7

Theoretical Analysis

MedKoo Cat#: 571136

Name: Furalaxyl

CAS#: 57646-30-7

Chemical Formula: C17H19NO4

Exact Mass: 301.1314

Molecular Weight: 301.34

Elemental Analysis: C, 67.76; H, 6.36; N, 4.65; O, 21.24

Price and Availability

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250mg USD 350.00 2 Weeks
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Related CAS #
No Data
Synonym
Furalaxyl; Fonganil; Fongarid; A5430; A-5430; A 5430
IUPAC/Chemical Name
DL-Alanine, N-(2,6-dimethylphenyl)-N-(2-furanylcarbonyl)-, methyl ester (9CI)
InChi Key
CIEXPHRYOLIQQD-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H19NO4/c1-11-7-5-8-12(2)15(11)18(13(3)17(20)21-4)16(19)14-9-6-10-22-14/h5-10,13H,1-4H3
SMILES Code
CC(C(OC)=O)N(C1=C(C)C=CC=C1C)C(C2=CC=CO2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 301.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sulimma L, Bullach A, Kusari S, Lamshöft M, Zühlke S, Spiteller M. Enantioselective degradation of the chiral fungicides metalaxyl and furalaxyl by Brevibacillus brevis. Chirality. 2013 Jun;25(6):336-40. doi: 10.1002/chir.22158. PubMed PMID: 23716265. 2: Qin F, Gao Y, Guo B, Xu P, Li J, Wang H. Enantioselective acute toxicity effects and bioaccumulation of furalaxyl in the earthworm (Eisenia foetida). Chirality. 2014 Jun;26(6):307-12. doi: 10.1002/chir.22323. Epub 2014 Apr 28. PubMed PMID: 24771637. 3: Qin F, Gao YX, Guo BY, Xu P, Li JZ, Wang HL. Environmental behavior of benalaxyl and furalaxyl enantiomers in agricultural soils. J Environ Sci Health B. 2014;49(10):738-46. doi: 10.1080/03601234.2014.929482. PubMed PMID: 25065825. 4: Iesce MR, Cermola F, Graziano ML, Montella S, Di Gioia L, Isidori M. Sensitized photooxygenation of the fungicide furalaxyl. Environ Sci Pollut Res Int. 2004;11(4):222-6. PubMed PMID: 15341311. 5: Zhang H, Wang X, Jin L, Qian M, Wang X, Xu H, Qi P, Wang Q, Wang M. Enantioselective determination of acylamino acid fungicides in vegetables and fruits by chiral liquid chromatography coupled with tandem mass spectrometry. J Sep Sci. 2012 Aug;35(15):1869-76. doi: 10.1002/jssc.201200063. Epub 2012 Jul 2. PubMed PMID: 22753298. 6: Jia W, Chu X, Zhang F. Multiresidue pesticide analysis in nutraceuticals from green tea extracts by comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry. J Chromatogr A. 2015 May 22;1395:160-6. doi: 10.1016/j.chroma.2015.03.071. Epub 2015 Apr 1. PubMed PMID: 25865796. 7: Yin J, Gao Y, Zhu F, Hao W, Xu Q, Wang H, Guo B. Enantiomerization and stereoselectivity in bioaccumulation of furalaxyl in Tenebrio molitor larvae. Ecotoxicol Environ Saf. 2017 Jul 22;145:244-249. doi: 10.1016/j.ecoenv.2017.07.041. [Epub ahead of print] PubMed PMID: 28743065. 8: Baggiani C, Baravalle P, Giraudi G, Tozzi C. Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine. J Chromatogr A. 2007 Feb 9;1141(2):158-64. Epub 2006 Dec 18. PubMed PMID: 17178127. 9: Yin J, Zhu F, Hao W, Xu Q, Chang J, Wang H, Guo B. Acylamino acid chiral fungicides on toxiciepigenetics in lambda DNA methylation. Food Chem Toxicol. 2017 Apr 26. pii: S0278-6915(17)30215-6. doi: 10.1016/j.fct.2017.04.038. [Epub ahead of print] PubMed PMID: 28456568. 10: Patel K, Fussell RJ, Goodall DM, Keely BJ. Analysis of pesticide residues in lettuce by large volume-difficult matrix introduction-gas chromatography-time of flight-mass spectrometry (LV-DMI-GC-TOF-MS). Analyst. 2003 Oct; 128(10):1228-31. Epub 2003 Sep 15. PubMed PMID: 14667157. 11: Huang CH, Stone AT. Hydrolysis of naptalam and structurally related amides: inhibition by dissolved metal ions and metal (hydr)oxide surfaces. J Agric Food Chem. 1999 Oct;47(10):4425-34. PubMed PMID: 10552829. 12: Albert-García JR, Icardo MC, Calatayud JM. Analytical strategy photodegradation/chemiluminescence/continuous-flow multicommutation methodology for the determination of the herbicide Propanil. Talanta. 2006 May 15;69(3):608-14. doi: 10.1016/j.talanta.2005.10.044. Epub 2005 Dec 15. PubMed PMID: 18970611.