SCR-4026 is an inhibitor of the nNOS-PSD-95 interaction. SCR-4026 exhibits neuroprotective activities in NMDA-induced or Oxygen and glucose deprivation (OGD)-induced neuronal damage in primary cortical neurons cultures, and ameliorates focal cerebral ischemic damage in rats subjected to middle cerebral artery occlusion (MCAO) and reperfusion. SCR-4026 also promotes neural stem cells to differentiate into neurons-like cells.
MedKoo Cat#: 561289
Name: SCR-4026
CAS#: Unknown
Chemical Formula: C14H12Cl2N2O2
Exact Mass: 310.0276
Molecular Weight: 311.16
Elemental Analysis: C, 54.04; H, 3.89; Cl, 22.79; N, 9.00; O, 10.28
The following data is based on the product molecular weight 311.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
