C012 Dihydrochloride is a novel small molecule compound which sensitized BRAF wild-type melanoma cells to vemurafenib. C012 Dihydrochloride significantly reduced melanoma cell viability, with limited toxicity for normal human fibroblasts.
MedKoo Cat#: 561275
Name: C012 Dihydrochloride
CAS#: 1219163-50-4
Chemical Formula: C23H30Cl2N4O
Exact Mass: 448.1797
Molecular Weight: 449.42
Elemental Analysis: C, 61.47; H, 6.73; Cl, 15.78; N, 12.47; O, 3.56
The following data is based on the product molecular weight 449.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
