MedKoo Cat#: 561234 | Name: CYM-5478
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CYM-5478 is a potent, selective agonist for S1P2. Under nutrient-deprivation stress produced by serum-starvation, CYM-5478 induced a statistically significant increase in the viability of C6 cells in a dose dependent manner at concentrations above 100 nM.

Chemical Structure

CYM-5478
CYM-5478
CAS#870762-83-7

Theoretical Analysis

MedKoo Cat#: 561234

Name: CYM-5478

CAS#: 870762-83-7

Chemical Formula: C21H19F3N2O2

Exact Mass: 388.1399

Molecular Weight: 388.40

Elemental Analysis: C, 64.94; H, 4.93; F, 14.67; N, 7.21; O, 8.24

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,450.00 2 Weeks
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Related CAS #
No Data
Synonym
CYM-5478; CYM 5478; CYM5478
IUPAC/Chemical Name
1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)pyridin-2-one
InChi Key
RGSGTUIDJXHTTO-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H19F3N2O2/c1-14-10-18(15(2)26(14)11-16-6-4-3-5-7-16)19(27)13-25-12-17(21(22,23)24)8-9-20(25)28/h3-10,12H,11,13H2,1-2H3
SMILES Code
O=C1C=CC(C(F)(F)F)=CN1CC(C2=C(C)N(CC3=CC=CC=C3)C(C)=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 388.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Deron R. Herr, Marie J. Y. Reolo, Yee Xin Peh, Wei Wang, Chang-Wook Lee, Rich Rivera, Ian C. Paterson & Jerold Chun. Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy. Scientific Reports 6, Article number: 24541 (2016) doi:10.1038/srep24541.