MedKoo Cat#: 571019 | Name: A 121

Description:

WARNING: This product is for research use only, not for human or veterinary use.

A 121 is a non-polyene antifungal antibiotic, produced by an unidentified strain of Streptomyces. It is active against a number of filamentous fungi including some plant and human pathogens. The presence of an alpha-ketol system in the molecule is required for A 121 to exhibit antibiotic properties.

Chemical Structure

A 121
A 121
CAS#68072-84-4

Theoretical Analysis

MedKoo Cat#: 571019

Name: A 121

CAS#: 68072-84-4

Chemical Formula: C18H30O5

Exact Mass: 326.2093

Molecular Weight: 326.43

Elemental Analysis: C, 66.23; H, 9.26; O, 24.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
A 121
IUPAC/Chemical Name
1-(2,3-dimethyl-2-(2-methylbut-3-en-2-yl)-2,3-dihydrofuran-3-yl)-3,5-dihydroxy-4-methoxyhexan-2-one
InChi Key
BSIAHHIPMGVHJM-UHFFFAOYSA-N
InChi Code
1S/C18H30O5/c1-8-16(3,4)18(6)17(5,9-10-23-18)11-13(20)14(21)15(22-7)12(2)19/h8-10,12,14-15,19,21H,1,11H2,2-7H3
SMILES Code
CC(C(C(C(=O)CC1(C=COC1(C)C(C)(C)C=C)C)O)OC)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 326.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Singh S, Samanta TB. A121--an antifungal compound from Streptomyces species. Microbios. 1992;71(288-289):217-24. PubMed PMID: 1479922. 2: Singh SK, Samanta TB. A121--a new antifungal antibiotic. Indian J Exp Biol. 1978 Jun;16(6):708-10. PubMed PMID: 700804.