WB403 is a TGR5 activator. WB403 significantly improves glucose tolerance and decreases fasting blood glucose, postprandial blood glucose and HbA1c in type 2 diabetic mice. WB403 also increases pancreatic β-cells and restores the normal distribution pattern of α-cell and β-cell in islets.
MedKoo Cat#: 561188
Name: WB403
CAS#: 1594041-84-5
Chemical Formula: C19H19BrN2OS
Exact Mass: 402.0401
Molecular Weight: 403.34
Elemental Analysis: C, 56.58; H, 4.75; Br, 19.81; N, 6.95; O, 3.97; S, 7.95
The following data is based on the product molecular weight 403.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
