Bz-rA phosphoramidite | nucleoside building block | CAS#104992-55-4

MedKoo Cat#: 128823 | Name: Bz-rA Phosphoramidite

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bz-rA phosphoramidite is an amine-protected nucleoside building block.

Chemical Structure

Bz-rA Phosphoramidite

CAS#104992-55-4

Theoretical Analysis

MedKoo Cat#: 128823

Name: Bz-rA Phosphoramidite

CAS#: 104992-55-4

Chemical Formula: C53H66N7O8PSi

Exact Mass: 987.4480

Molecular Weight: 988.21

Elemental Analysis: C, 64.42; H, 6.73; N, 9.92; O, 12.95; P, 3.13; Si, 2.84

Price and Availability

Size	Price	Availability
1mg	USD 350.00	2 Weeks
5mg	USD 750.00	2 Weeks
10mg	USD 1,250.00	2 Weeks

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Related CAS #

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Synonym

Bz-rA Phosphoramidite; BzrA Phosphoramidite; Bz rA Phosphoramidite

IUPAC/Chemical Name

(2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChi Key

FFXHNCNNHASXCT-RFMFGJHUSA-N

InChi Code

InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1

SMILES Code

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]([C@H](N5C6=NC=NC(NC(C7=CC=CC=C7)=O)=C6N=C5)O4)O[Si](C)(C)C(C)(C)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 988.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Ablasser, A., Goldeck, M., Cavlar, T., et al. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 498(7454), 380-384 (2013).