AKOS-22, also known as AKOS-022075291, is a VDAC1 inhibitor. AKOS-22 inhibits both VDAC1 oligomerization and apoptosis in a concentration-dependent manner.
MedKoo Cat#: 561047
Name: AKOS-22
CAS#: 878983-38-1
Chemical Formula: C22H21ClF3N3O3
Exact Mass: 467.1224
Molecular Weight: 467.87
Elemental Analysis: C, 56.48; H, 4.52; Cl, 7.58; F, 12.18; N, 8.98; O, 10.26
The following data is based on the product molecular weight 467.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
