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MedKoo Cat#: 540085 | Name: Clopidol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clopidol is coccidiostat used to treat parasite infections in veterinary medicine.

Chemical Structure

Clopidol
Clopidol
CAS#2971-90-6

Theoretical Analysis

MedKoo Cat#: 540085

Name: Clopidol

CAS#: 2971-90-6

Chemical Formula: C7H7Cl2NO

Exact Mass: 190.9905

Molecular Weight: 192.03

Elemental Analysis: C, 43.78; H, 3.67; Cl, 36.92; N, 7.29; O, 8.33

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
BRN 1527826; BRN-1527826; BRN1527826; Clopidolo; HSDB 7907; HSDB-7907; HSDB7907; Lerbek; Methylchloropindol; WR 61112; WR61112; WR-61112
IUPAC/Chemical Name
3,5-dichloro-2,6-dimethylpyridin-4-ol
InChi Key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
SMILES Code
OC1=C(Cl)C(C)=NC(C)=C1Cl
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 192.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ali AM, Seddiek ShA, Khater HF. Effect of butyrate, clopidol and their combination on the performance of broilers infected with Eimeria maxima. Br Poult Sci. 2014;55(4):474-82. doi: 10.1080/00071668.2014.920488. Epub 2014 Sep 10. PubMed PMID: 25207431. 2: Song W, Hu Y, Han F, Lü Y, Zheng P, Zhou F, Chen X, Qiu J, Zhou X. [Simultaneous determination of clopidol, sulfonamide and quinolone residues in chickens by ultra performance liquid chromatography-tandem mass spectrometry]. Se Pu. 2013 Dec;31(12):1161-6. Chinese. PubMed PMID: 24669706. 3: Ekström LG, Kuivinen J. Gas chromatographic determination of clopidol in chicken tissues. J Assoc Off Anal Chem. 1984 Sep-Oct;67(5):955-7. PubMed PMID: 6501161. 4: Ekström LG, Slanina P, Dahlström-King L. Tissue residues of clopidol (3,5-dichloro-2,6-dimethyl-4-pyridinol) in chickens in relation to withdrawal times. Food Addit Contam. 1984 Jan-Mar;1(1):17-22. PubMed PMID: 6537344. 5: Yang W, Xu J, Yang G, Ding T, Qi J, Liu H, Shen C, Wu B, Yu S. [Determination of clopidol residue in poultry products by liquid chromatography-electrospray ion trap tandem mass spectrometry]. Se Pu. 2009 Mar;27(2):144-8. Chinese. PubMed PMID: 19626838. 6: Chapman HD. Eimeria tenella: experimental studies on the development of resistance to amprolium, clopidol and methyl benzoquate. Parasitology. 1978 Apr;76(2):177-83. PubMed PMID: 274682. 7: Liu X, Su Y, Fang B, Ding H, He L, Zeng Z, Chen Z. [Determination of clopidol residues in chicken muscle by gas chromatography-mass spectrometry]. Se Pu. 2009 Jan;27(1):86-90. Chinese. PubMed PMID: 19449548. 8: Joyner LP, Norton CC. The activity of methyl benzoquate and clopidol against Eimeria maxima: synergy and drug resistance. Parasitology. 1978 Jun;76(3):369-77. PubMed PMID: 275786. 9: Fry M, Williams RB. Effects of decoquinate and clopidol on electron transport in mitochondria of Eimeria tenella (Apicomplexa: Coccidia). Biochem Pharmacol. 1984 Jan 15;33(2):229-40. PubMed PMID: 6704148. 10: Arakawa A, Tanaka Y, Baba E, Fukata T. Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts. Vet Parasitol. 1991 Jan;38(1):55-60. PubMed PMID: 2024430. 11: Peeters JE, Geeroms R, Varewyck H, Bouquet Y, Lampo P, Halen P. Immunity and effect of clopidol/methyl benzoquate and robenidine before and after weaning on rabbit coccidiosis in the field. Res Vet Sci. 1983 Sep;35(2):211-6. PubMed PMID: 6356256. 12: Suzuki E, Matsuda M, Momose A, Namekata M. Improved method for gas-liquid chromatographic determination of clopidol in chicken tissues. J Assoc Off Anal Chem. 1980 Nov;63(6):1211-4. PubMed PMID: 7451382. 13: Pang GF, Cao YZ, Fan CL, Zhang JJ, Li XM, MacNeil JD. Determination of clopidol residues in chicken tissues by liquid chromatography: collaborative study. J AOAC Int. 2003 Jul-Aug;86(4):685-93. PubMed PMID: 14509425. 14: Mtema CA, Nakazawa H, Takabatake E. Rapid liquid chromatographic determination of clopidol in chicken muscles. J Assoc Off Anal Chem. 1984 Mar-Apr;67(2):334-6. PubMed PMID: 6725202. 15: Rathinam T, Chapman HD. Sensitivity of isolates of Eimeria from turkey flocks to the anticoccidial drugs amprolium, clopidol, diclazuril, and monensin. Avian Dis. 2009 Sep;53(3):405-8. PubMed PMID: 19848080. 16: Dusi G, Faggionato E, Gamba V, Baiguera A. Determination of nicarbazin and clopidol in poultry feeds by liquid chromatography. J Chromatogr A. 2000 Jun 16;882(1-2):79-84. PubMed PMID: 10895934. 17: Fang B, Su Y, Ding H, Zhang J, He L. Determination of residual clopidol in chicken muscle by capillary gas chromatography-negative chemical ionization-mass spectrometry. Anal Sci. 2009 Oct;25(10):1203-6. PubMed PMID: 19822963. 18: Pang GF, Cao YZ, Fan CL, Zhang JJ, Li XM. Determination of clopidol residues in chicken tissues by liquid chromatography: part I. Optimization of analytical conditions and comparison with AOAC gas chromatography method. J AOAC Int. 2001 Sep-Oct;84(5):1337-42. PubMed PMID: 11601450. 19: Coats JR, Metcalf RL, Lu PY, Brown DD, Williams JF, Hansen LG. Model ecosystem evaluation of the environmental impacts of the veterinary drugs phenothiazine, sulfamethazine, clopidol, and diethylstilbestrol. Environ Health Perspect. 1976 Dec;18:167-79. PubMed PMID: 1037611; PubMed Central PMCID: PMC1475296. 20: Pang GF, Cao YZ, Fan CL, Zhang JJ, Li XM, Wang C. Determination of clopidol residues in chicken tissues by high-performance liquid chromatography-mass spectrometry. J Chromatogr A. 2000 Jun 16;882(1-2):85-8. PubMed PMID: 10895935.