MedKoo Cat#: 526017 | Name: Fenpyroximate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fenpyroximate is an acaricide and insecticide, blocking the mitochondrial electron transport in complex I.

Chemical Structure

Fenpyroximate
Fenpyroximate
CAS#134098-61-6

Theoretical Analysis

MedKoo Cat#: 526017

Name: Fenpyroximate

CAS#: 134098-61-6

Chemical Formula: C24H27N3O4

Exact Mass: 421.2000

Molecular Weight: 421.50

Elemental Analysis: C, 68.39; H, 6.46; N, 9.97; O, 15.18

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
1g USD 850.00 2 Weeks
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Related CAS #
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Synonym
Fenpyroximate; fenperoximate; FujiMite; NNI 850; NNI850; NNI-850
IUPAC/Chemical Name
4-[[[(E)-[(1,3-Dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoic Acid tert-Butyl Ester
InChi Key
YYJNOYZRYGDPNH-MFKUBSTISA-N
InChi Code
InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+
SMILES Code
O=C(OC(C)(C)C)C1=CC=C(CO/N=C/C2=C(OC3=CC=CC=C3)N(C)N=C2C)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 421.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ozawa R, Endo H, Iijima M, Sugimoto K, Takabayashi J, Gotoh T, Arimura GI. Intraspecific variation among Tetranychid mites for ability to detoxify and to induce plant defenses. Sci Rep. 2017 Feb 27;7:43200. doi: 10.1038/srep43200. PubMed PMID: 28240222; PubMed Central PMCID: PMC5327432. 2: Malima R, Emidi B, Messenger LA, Oxborough RM, Batengana B, Sudi W, Weston S, Mtove G, Mugasa JP, Mosha FW, Rowland MW, Kisinza W. Experimental hut evaluation of a novel long-lasting non-pyrethroid durable wall lining for control of pyrethroid-resistant Anopheles gambiae and Anopheles funestus in Tanzania. Malar J. 2017 Feb 17;16(1):82. doi: 10.1186/s12936-017-1710-6. PubMed PMID: 28212636; PubMed Central PMCID: PMC5316163. 3: Bajda S, Dermauw W, Panteleri R, Sugimoto N, Douris V, Tirry L, Osakabe M, Vontas J, Van Leeuwen T. A mutation in the PSST homologue of complex I (NADH:ubiquinone oxidoreductase) from Tetranychus urticae is associated with resistance to METI acaricides. Insect Biochem Mol Biol. 2017 Jan;80:79-90. doi: 10.1016/j.ibmb.2016.11.010. Epub 2016 Dec 2. PubMed PMID: 27919778. 4: Ma J, Yao Z, Hou L, Lu W, Yang Q, Li J, Chen L. Metal organic frameworks (MOFs) for magnetic solid-phase extraction of pyrazole/pyrrole pesticides in environmental water samples followed by HPLC-DAD determination. Talanta. 2016 Dec 1;161:686-692. doi: 10.1016/j.talanta.2016.09.035. Epub 2016 Sep 12. PubMed PMID: 27769466. 5: Lima DB, Melo JW, Gondim MG Jr, Guedes RN, Oliveira JE. Population-level effects of abamectin, azadirachtin and fenpyroximate on the predatory mite Neoseiulus baraki. Exp Appl Acarol. 2016 Oct;70(2):165-77. doi: 10.1007/s10493-016-0074-x. Epub 2016 Aug 5. PubMed PMID: 27495808. 6: Dunn JA, Prickett JC, Collins DA, Weaver RJ. Primary screen for potential sheep scab control agents. Vet Parasitol. 2016 Jul 15;224:68-76. doi: 10.1016/j.vetpar.2016.05.019. Epub 2016 May 17. PubMed PMID: 27270393. 7: Kanga LH, Eason J, Haseeb M, Qureshi J, Stansly P. Monitoring for Insecticide Resistance in Asian Citrus Psyllid (Hemiptera: Psyllidae) Populations in Florida. J Econ Entomol. 2016 Apr;109(2):832-6. PubMed PMID: 26709293. 8: Lopez L, Smith HA, Hoy MA, Bloomquist JR. Acute Toxicity and Sublethal Effects of Fenpyroximate to Amblyseius swirskii (Acari: Phytoseiidae). J Econ Entomol. 2015 Jun;108(3):1047-53. doi: 10.1093/jee/tov033. Epub 2015 Mar 18. PubMed PMID: 26470228. 9: Lira AC, Zanardi OZ, Beloti VH, Bordini GP, Yamamoto PT, Parra JR, Carvalho GA. Lethal and Sublethal Impacts of Acaricides on Tamarixia radiata (Hemiptera: Eulophidae), an Important Ectoparasitoid of Diaphorina citri (Hemiptera: Liviidae). J Econ Entomol. 2015 Oct;108(5):2278-88. doi: 10.1093/jee/tov189. Epub 2015 Jul 3. PubMed PMID: 26453716. 10: Riga M, Myridakis A, Tsakireli D, Morou E, Stephanou EG, Nauen R, Van Leeuwen T, Douris V, Vontas J. Functional characterization of the Tetranychus urticae CYP392A11, a cytochrome P450 that hydroxylates the METI acaricides cyenopyrafen and fenpyroximate. Insect Biochem Mol Biol. 2015 Oct;65:91-9. doi: 10.1016/j.ibmb.2015.09.004. Epub 2015 Sep 9. PubMed PMID: 26363294. 11: Nakajima T, Tsuruoka Y, Kanda M, Hayashi H, Hashimoto T, Matsushima Y, Yoshikawa S, Nagano C, Okutomi Y, Takano I. Determination and surveillance of nine acaricides and one metabolite in honey by liquid chromatography-tandem mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(7):1099-104. doi: 10.1080/19440049.2015.1050460. Epub 2015 Jun 8. PubMed PMID: 25967980. 12: Murai M, Murakami S, Ito T, Miyoshi H. Amilorides bind to the quinone binding pocket of bovine mitochondrial complex I. Biochemistry. 2015 May 5;54(17):2739-46. doi: 10.1021/acs.biochem.5b00187. Epub 2015 Apr 16. PubMed PMID: 25849763. 13: Lima DB, Melo JW, Gondim MG Jr, Guedes RN, Oliveira JE, Pallini A. Acaricide-impaired functional predation response of the phytoseiid mite Neoseiulus baraki to the coconut mite Aceria guerreronis. Ecotoxicology. 2015 Jul;24(5):1124-30. doi: 10.1007/s10646-015-1459-z. Epub 2015 Apr 7. PubMed PMID: 25847106. 14: Masuya T, Murai M, Morisaka H, Miyoshi H. Pinpoint chemical modification of Asp160 in the 49 kDa subunit of bovine mitochondrial complex I via a combination of ligand-directed tosyl chemistry and click chemistry. Biochemistry. 2014 Dec 16;53(49):7816-23. doi: 10.1021/bi501342w. Epub 2014 Dec 2. PubMed PMID: 25419630. 15: Iwassaki LA, Sato ME, Calegario FF, Poletti M, Maia Ade H. Comparison of conventional and integrated programs for control of Tetranychus urticae (Acari: Tetranychidae). Exp Appl Acarol. 2015 Feb;65(2):205-17. doi: 10.1007/s10493-014-9853-4. Epub 2014 Oct 4. PubMed PMID: 25280557. 16: Li-Byarlay H, Rittschof CC, Massey JH, Pittendrigh BR, Robinson GE. Socially responsive effects of brain oxidative metabolism on aggression. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12533-7. doi: 10.1073/pnas.1412306111. Epub 2014 Aug 4. PubMed PMID: 25092297; PubMed Central PMCID: PMC4151721. 17: Ma J, Lu X, Xia Y, Yan F. Determination of pyrazole and pyrrole pesticides in environmental water samples by solid-phase extraction using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography. J Chromatogr Sci. 2015 Feb;53(2):380-4. doi: 10.1093/chromsci/bmu055. Epub 2014 Jun 19. PubMed PMID: 24947489. 18: Azevedo LH, Moraes GJ, Yamamoto PT, Zanardi OZ. Development of a methodology and evaluation of pesticides against Aceria litchii and its predator Phytoseius intermedius (Acari: Eriophyidae, Phytoseiidae). J Econ Entomol. 2013 Oct;106(5):2183-9. PubMed PMID: 24224263. 19: Zhang J, Liang Z, Guo H, Gao P, Lu R, Zhou W, Zhang S, Gao H. Ionic liquid-based totally organic solvent-free emulsification microextraction coupled with high performance liquid chromatography for the determination of three acaricides in fruit juice. Talanta. 2013 Oct 15;115:556-62. doi: 10.1016/j.talanta.2013.06.010. Epub 2013 Jun 14. PubMed PMID: 24054632. 20: Xu D, Lu S, Chen D, Lan J, Zhang Z, Yang F, Zhou Y. [Determination of ten pesticides of pyrazoles and pyrroles in tea by accelerated solvent extraction coupled with gas chromatography-tandem mass spectrometry]. Se Pu. 2013 Mar;31(3):218-22. Chinese. PubMed PMID: 23785993.