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MedKoo Cat#: 461773 | Name: Sanguiin h 11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sanguiin h 11 is a compound purified from the plant Sanguisorba officinalis and has proven to be a potent inhibitor of chemoattractant-dependent and independent neutrophil movement.

Chemical Structure

Sanguiin h 11
Sanguiin h 11
CAS#96292-46-5

Theoretical Analysis

MedKoo Cat#: 461773

Name: Sanguiin h 11

CAS#: 96292-46-5

Chemical Formula: C41H28O26

Exact Mass: 936.0869

Molecular Weight: 936.64

Elemental Analysis: C, 52.58; H, 3.01; O, 44.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Sanguiin h 11; Sanguiin H-11;
IUPAC/Chemical Name
(6aR,7S,8aR,21aR,21bS)-1,2,3,13,14,15,16,17,18,25,26,27-dodecahydroxy-5,11,20,23-tetraoxo-5,6a,7,8a,9,11,20,21a,21b,23-decahydrodibenzo[g,i]dibenzo[6',7':8',9'][1,4]dioxecino[2',3':4,5]pyrano[3,2-b][1,5]dioxacycloundecin-7-yl 3,4,5-trihydroxybenzoate
InChi Key
SWRFKGRMQVLMKA-JIZJWZDPSA-N
InChi Code
InChI=1S/C41H28O26/c42-13-1-8(2-14(43)24(13)48)36(57)67-41-35-34(65-39(60)11-5-17(46)27(51)31(55)22(11)23-12(40(61)66-35)6-18(47)28(52)32(23)56)33-19(63-41)7-62-37(58)9-3-15(44)25(49)29(53)20(9)21-10(38(59)64-33)4-16(45)26(50)30(21)54/h1-6,19,33-35,41-56H,7H2/t19-,33-,34+,35-,41+/m1/s1
SMILES Code
O=C(O[C@H](O1)[C@@](OC(C2=CC(O)=C(O)C(O)=C2C3=C(O)C(O)=C(O)C=C34)=O)([H])[C@@]([C@]([C@@]1([H])COC(C5=CC(O)=C(O)C(O)=C5C6=C(O)C(O)=C(O)C=C67)=O)([H])OC7=O)([H])OC4=O)C8=CC(O)=C(O)C(O)=C8
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 936.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Konishi K, Urada M, Adachi I, Tanaka T. Inhibitory effect of sanguiin H-11 on chemotaxis of neutrophil. Biol Pharm Bull. 2000 Feb;23(2):213-8. PubMed PMID: 10706387. 2: Yokozawa T, Chen CP, Tanaka T, Kitani K. A study on the nitric oxide production-suppressing activity of sanguisorbae radix components. Biol Pharm Bull. 2000 Jun;23(6):717-22. PubMed PMID: 10864022.

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