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MedKoo Cat#: 526003 | Name: Lifibrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lifibrate is an inhibitor of cholinephosphotransferase (CPT), phosphatidyl-N-methylethanolamine N-methyltransferase (PME-NMT), and phosphatidyl-N,N-dimethylethanolamine N-methyltransferase (PDE-NMT).

Chemical Structure

Lifibrate
Lifibrate
CAS#22204-91-7

Theoretical Analysis

MedKoo Cat#: 526003

Name: Lifibrate

CAS#: 22204-91-7

Chemical Formula: C20H21Cl2NO4

Exact Mass: 409.0848

Molecular Weight: 410.29

Elemental Analysis: C, 58.55; H, 5.16; Cl, 17.28; N, 3.41; O, 15.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lifibrate
IUPAC/Chemical Name
(1-Methylpiperidin-4-yl) 2,2-bis(4-chlorophenoxy)acetate
InChi Key
QDGIAPPCJRFVEK-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H21Cl2NO4/c1-23-12-10-18(11-13-23)25-19(24)20(26-16-6-2-14(21)3-7-16)27-17-8-4-15(22)5-9-17/h2-9,18,20H,10-13H2,1H3
SMILES Code
O=C(OC1CCN(C)CC1)C(OC2=CC=C(Cl)C=C2)OC3=CC=C(Cl)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Percy AK, Moore JF, Waechter CJ. Phosphoglyceride biosynthesis by brain microsomes: centrophenoxine, SaH-42-348, and DH-990 inhibit phospholipid N-methylation. Arch Biochem Biophys. 1984 Nov 15;235(1):18-25. PubMed PMID: 6437335. 2: Arnold A, McAuliff MP, Beyler AL. Metabolic effects of a new hypolipidemic agent, ciprofibrate. J Pharm Sci. 1979 Dec;68(12):1557-8. PubMed PMID: 529054.