YIL781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM). YIL781 displays no significant affinity for the motilin receptor (Ki = 6 μM). It bBlocks the effects of ghrelin on insulin secretion both in vivo and in vitro.
MedKoo Cat#: 532981
Name: YIL781 HCl
CAS#: 1640226-17-0 (HCl)
Chemical Formula: C24H29ClFN3O2
Exact Mass: 409.2166
Molecular Weight: 445.96
Elemental Analysis: C, 64.64; H, 6.55; Cl, 7.95; F, 4.26; N, 9.42; O, 7.18
The following data is based on the product molecular weight 445.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
