CPT | CAS#35873-49-5

MedKoo Cat#: 525922 | Name: CPT

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CPT is a potent adenosine A1 receptor antagonist.

Chemical Structure

CPT

CAS#35873-49-5

Theoretical Analysis

MedKoo Cat#: 525922

Name: CPT

CAS#: 35873-49-5

Chemical Formula: C12H16N4O2

Exact Mass: 248.1273

Molecular Weight: 248.29

Elemental Analysis: C, 58.05; H, 6.50; N, 22.57; O, 12.89

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 385.00	2 Weeks

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Related CAS #

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Synonym

CPT; 8-Cyclopentyltheophylline; PD 116600; PD116600; PD-116600; NSC 101806; NSC101806; NSC-101806

IUPAC/Chemical Name

8-Cyclopentyl-1,3-dimethylxanthine

InChi Key

SCVHFRLUNIOSGI-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H16N4O2/c1-15-10-8(11(17)16(2)12(15)18)13-9(14-10)7-5-3-4-6-7/h7H,3-6H2,1-2H3,(H,13,14)

SMILES Code

O=C(N1C)N(C)C2=C(NC(C3CCCC3)=N2)C1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 248.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Liu Y, Mei H, Zhu G, Liu K, Wu J, Tang J, He R. Congenital pseudarthrosis of the tibia in children: should we defer surgery until 3 years old? J Pediatr Orthop B. 2017 May 30. doi: 10.1097/BPB.0000000000000468. [Epub ahead of print] PubMed PMID: 28562492. 2: Vigouroux F, Mezzadri G, Parot R, Gazarian A, Pannier S, Chotel F. Vascularised Fibula or Induced Membrane to Treat Congenital Pseudarthrosis of the Tibia: A Multicentre Study of 18 Patients with a Mean 9.5-Year Follow-Up. Orthop Traumatol Surg Res. 2017 May 27. pii: S1877-0568(17)30147-0. doi: 10.1016/j.otsr.2017.05.005. [Epub ahead of print] PubMed PMID: 28559144. 3: Sanche S, Sheehan N, Mesplède T, Wainberg MA, Li J, Nekka F. A Mathematical Model to Predict HIV Virological Failure and Elucidate the Role of Lymph Node Drug Penetration. CPT Pharmacometrics Syst Pharmacol. 2017 May 27. doi: 10.1002/psp4.12200. [Epub ahead of print] PubMed PMID: 28556627. 4: Hallow KM, Gebremichael Y. A Quantitative Systems Physiology Model of Renal Function and Blood Pressure Regulation: Application in Salt-Sensitive Hypertension. CPT Pharmacometrics Syst Pharmacol. 2017 May 27. doi: 10.1002/psp4.12177. [Epub ahead of print] PubMed PMID: 28556624. 5: Gennemark P, Trägårdh M, Lindén D, Ploj K, Johansson A, Turnbull A, Carlsson B, Antonsson M. Translational Modeling to Guide Study Design and Dose Choice in Obesity Exemplified by AZD1979, a Melanin-concentrating Hormone Receptor 1 Antagonist. CPT Pharmacometrics Syst Pharmacol. 2017 May 27. doi: 10.1002/psp4.12199. [Epub ahead of print] PubMed PMID: 28556607. 6: Krause A, Machacek M, Lott D, Hurst N, Bruderer S, Dingemanse J. Population Modeling of Selexipag Pharmacokinetics and Clinical Response Parameters in Patients With Pulmonary Arterial Hypertension. CPT Pharmacometrics Syst Pharmacol. 2017 May 27. doi: 10.1002/psp4.12202. [Epub ahead of print] PubMed PMID: 28556581. 7: Shoji S, Suzuki A, Conrado DJ, Peterson MC, Hey-Hadavi J, McCabe D, Rojo R, Tammara BK. Dissociated Agonist of Glucocorticoid Receptor or Prednisone for Active Rheumatoid Arthritis: Effects on P1NP and Osteocalcin Pharmacodynamics. CPT Pharmacometrics Syst Pharmacol. 2017 May 27. doi: 10.1002/psp4.12201. [Epub ahead of print] PubMed PMID: 28556506. 8: Wu X, Tan YJ, Toh HT, Nguyen LH, Kho SH, Chew SY, Yoon HS, Liu XW. Stimuli-responsive multifunctional glyconanoparticle platforms for targeted drug delivery and cancer cell imaging. Chem Sci. 2017 May 1;8(5):3980-3988. doi: 10.1039/c6sc05251g. Epub 2017 Mar 30. PubMed PMID: 28553540; PubMed Central PMCID: PMC5433505. 9: Wang LJ, Chou MC, Chou WJ, Lee MJ, Lee SY, Lin PY, Lee YH, Yang YH, Yen CF. Potential role of pre- and postnatal testosterone levels in attention-deficit/hyperactivity disorder: is there a sex difference? Neuropsychiatr Dis Treat. 2017 May 16;13:1331-1339. doi: 10.2147/NDT.S136717. eCollection 2017. PubMed PMID: 28553119; PubMed Central PMCID: PMC5439987. 10: Tallman JE, Pearce SM, Kuchta K, Helfand BT, Eggener SE. Impact of Perioperative Infection on Cancer-Specific Survival after Nephrectomy for Renal Cell Carcinoma. J Urol. 2017 May 24. pii: S0022-5347(17)74438-2. doi: 10.1016/j.juro.2017.05.070. [Epub ahead of print] PubMed PMID: 28551443. 11: Nieto J, Khaleel H, Challita Y, Jimenez M, Baron TH, Walters L, Hathaway K, Patel K, Lankarani A, Herman M, Holloman D, Saab S. EUS-guided fine-needle core liver biopsy using a novel 19G needle with modified one pass, one actuation wet suction technique. Gastrointest Endosc. 2017 May 24. pii: S0016-5107(17)31916-8. doi: 10.1016/j.gie.2017.05.013. [Epub ahead of print] PubMed PMID: 28551024. 12: Sharland MJ, Waring SC, Johnson BP, Taran AM, Rusin TA, Pattock AM, Palcher JA. Further examination of embedded performance validity indicators for the Conners' Continuous Performance Test and Brief Test of Attention in a large outpatient clinical sample. Clin Neuropsychol. 2017 May 26:1-11. doi: 10.1080/13854046.2017.1332240. [Epub ahead of print] PubMed PMID: 28548557. 13: Hallow KM, Gebremichael Y. A quantitative systems physiology model of renal function and blood pressure regulation: Model description. CPT Pharmacometrics Syst Pharmacol. 2017 May 26. doi: 10.1002/psp4.12178. [Epub ahead of print] PubMed PMID: 28548387. 14: Ortmeyer HK, Goldberg AP, Ryan AS. Exercise with weight loss improves adipose tissue and skeletal muscle markers of fatty acid metabolism in postmenopausal women. Obesity (Silver Spring). 2017 May 26. doi: 10.1002/oby.21877. [Epub ahead of print] PubMed PMID: 28547918. 15: Byon W, Sweeney K, Frost C, Boyd RA. Population Pharmacokinetics, Pharmacodynamics, and Exploratory Exposure-Response Analyses of Apixaban in Subjects Treated for Venous Thromboembolism. CPT Pharmacometrics Syst Pharmacol. 2017 May;6(5):340-349. doi: 10.1002/psp4.12184. PubMed PMID: 28547774; PubMed Central PMCID: PMC5445237. 16: Natesan S, Sugumaran A, Ponnusamy C, Thiagarajan V, Palanichamy R, Kandasamy R. Chitosan stabilized camptothecin nanoemulsions: development, evaluation and biodistribution in preclinical breast cancer animal mode. Int J Biol Macromol. 2017 May 22. pii: S0141-8130(16)32673-3. doi: 10.1016/j.ijbiomac.2017.05.127. [Epub ahead of print] PubMed PMID: 28545970. 17: Jang HS, Shin WJ, Lee JE, Do JT. CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function. Genes (Basel). 2017 May 23;8(6). pii: E148. doi: 10.3390/genes8060148. Review. PubMed PMID: 28545252. 18: Kim SM, Lee B, An HJ, Kim DH, Park KC, Noh SG, Chung KW, Lee EK, Kim KM, Kim DH, Kim SJ, Chun P, Lee HJ, Moon HR, Chung HY. Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget. 2017 May 8. doi: 10.18632/oncotarget.17695. [Epub ahead of print] PubMed PMID: 28545035. 19: Lu D, Gillespie WR, Girish S, Agarwal P, Li C, Hirata J, Chu YW, Kagedal M, Leon L, Maiya V, Jin JY. Time-to-Event Analysis of Polatuzumab Vedotin-Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens. CPT Pharmacometrics Syst Pharmacol. 2017 May 23. doi: 10.1002/psp4.12192. [Epub ahead of print] PubMed PMID: 28544534. 20: Draus JM Jr. A Multidisciplinary Child Protection Team Improves the Care of Nonaccidental Trauma Patients. Am Surg. 2017 May 1;83(5):477-481. PubMed PMID: 28541857.