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MedKoo Cat#: 525874 | Name: CENTA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CENTA is a chromogenic substrate for studying beta-lactamases.

Chemical Structure

CENTA
CAS#80072-86-2

Theoretical Analysis

MedKoo Cat#: 525874

Name: CENTA

CAS#: 80072-86-2

Chemical Formula: C21H17N3O8S3

Exact Mass: 535.0178

Molecular Weight: 535.56

Elemental Analysis: C, 47.10; H, 3.20; N, 7.85; O, 23.90; S, 17.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CENTA
IUPAC/Chemical Name
(6R,7R)-3-[(3-Carboxy-4-nitrophenyl)sulfanylmethyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChi Key
PFVWVVUSAORMBB-VQIMIIECSA-N
InChi Code
InChI=1S/C21H17N3O8S3/c25-15(7-11-2-1-5-33-11)22-16-18(26)23-17(21(29)30)10(9-35-19(16)23)8-34-12-3-4-14(24(31)32)13(6-12)20(27)28/h1-6,16,19H,7-9H2,(H,22,25)(H,27,28)(H,29,30)/t16-,19-/m1/s1
SMILES Code
O=C(C(N12)=C(CSC3=CC=C([N+]([O-])=O)C(C(O)=O)=C3)CS[C@]2([H])[C@H](NC(CC4=CC=CS4)=O)C1=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 535.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lansac E, Di Centa I. Reply. Ann Thorac Surg. 2017 May;103(5):1681. doi: 10.1016/j.athoracsur.2016.10.029. PubMed PMID: 28431706. 2: Lansac E, Di Centa I, Sleilaty G, Lejeune S, Berrebi A, Zacek P, Debauchez M. Remodeling root repair with an external aortic ring annuloplasty. J Thorac Cardiovasc Surg. 2017 May;153(5):1033-1042. doi: 10.1016/j.jtcvs.2016.12.031. Epub 2017 Jan 11. PubMed PMID: 28187973. 3: Romero-Pareja PM, Aragon CA, Quiroga JM, Coello MD. Evaluation of a biological wastewater treatment system combining an OSA process with ultrasound for sludge reduction. Ultrason Sonochem. 2017 May;36:336-342. doi: 10.1016/j.ultsonch.2016.12.006. Epub 2016 Dec 10. PubMed PMID: 28069218. 4: Kontuľ I, Ješkovský M, Kaizer J, Šivo A, Richtáriková M, Povinec PP, Čech P, Steier P, Golser R. Radiocarbon concentration in tree-ring samples collected in the south-west Slovakia (1974-2013). Appl Radiat Isot. 2016 Dec 3. pii: S0969-8043(16)30518-8. doi: 10.1016/j.apradiso.2016.12.001. [Epub ahead of print] PubMed PMID: 27988243. 5: Lansac E, Di Centa I, Sleilaty G, Lejeune S, Khelil N, Berrebi A, Diakov C, Mankoubi L, Malergue MC, Noghin M, Zannis K, Salvi S, Dervanian P, Debauchez M. Long-term results of external aortic ring annuloplasty for aortic valve repair. Eur J Cardiothorac Surg. 2016 Aug;50(2):350-60. doi: 10.1093/ejcts/ezw070. PubMed PMID: 27440158. 6: Mookhoek A, Korteland NM, Arabkhani B, Di Centa I, Lansac E, Bekkers JA, Bogers AJ, Takkenberg JJ. Bentall Procedure: A Systematic Review and Meta-Analysis. Ann Thorac Surg. 2016 May;101(5):1684-9. doi: 10.1016/j.athoracsur.2015.10.090. Epub 2016 Feb 6. Review. PubMed PMID: 26857635. 7: Centa M, Gruber S, Nilsson D, Polyzos KA, Johansson DK, Hansson GK, Ketelhuth DF, Binder CJ, Malin S. Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene. Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):25-36. doi: 10.1161/ATVBAHA.115.305990. Epub 2015 Nov 12. PubMed PMID: 26564818; PubMed Central PMCID: PMC4684249. 8: Arabkhani B, Mookhoek A, Di Centa I, Lansac E, Bekkers JA, De Lind Van Wijngaarden R, Bogers AJ, Takkenberg JJ. Reported Outcome After Valve-Sparing Aortic Root Replacement for Aortic Root Aneurysm: A Systematic Review and Meta-Analysis. Ann Thorac Surg. 2015 Sep;100(3):1126-31. doi: 10.1016/j.athoracsur.2015.05.093. Epub 2015 Jul 28. Review. PubMed PMID: 26228603. 9: Fauchier L, Greenlaw N, Ferrari R, Ford I, Fox KM, Tardif JC, Tendera M, Steg PG; CLARIFY Investigators.. Use of Anticoagulants and Antiplatelet Agents in Stable Outpatients with Coronary Artery Disease and Atrial Fibrillation. International CLARIFY Registry. PLoS One. 2015 Apr 27;10(4):e0125164. doi: 10.1371/journal.pone.0125164. eCollection 2015. PubMed PMID: 25915904; PubMed Central PMCID: PMC4411156. 10: Khelil N, Sleilaty G, Palladino M, Fouda M, Escande R, Debauchez M, Di Centa I, Lansac E. Surgical anatomy of the aortic annulus: landmarks for external annuloplasty in aortic valve repair. Ann Thorac Surg. 2015 Apr;99(4):1220-6. doi: 10.1016/j.athoracsur.2014.12.034. Epub 2015 Feb 27. PubMed PMID: 25728963. 11: Romero P, Coello MD, Aragón CA, Eusebi AL. Sludge reduction at low ozone doses: predictive effects and full-scale study. Water Sci Technol. 2015;71(2):191-6. doi: 10.2166/wst.2014.486. PubMed PMID: 25633941. 12: Lansac E, Bouchot O, Arnaud Crozat E, Hacini R, Doguet F, Demaria R, Leguerrier A, Jouan J, Chatel D, Lopez S, Folliguet T, Acar C, Leprince P, Langanay T, Jegaden O, Bessou JP, Albat B, Latremouille C, Fabiani JN, Fayad G, Fleury JP, Pasquet B, Debauchez M, Di Centa I, Tubach F. Standardized approach to valve repair using an expansible aortic ring versus mechanical Bentall: early outcomes of the CAVIAAR multicentric prospective cohort study. J Thorac Cardiovasc Surg. 2015 Feb;149(2 Suppl):S37-45. doi: 10.1016/j.jtcvs.2014.07.105. Epub 2014 Aug 12. PubMed PMID: 25240525. 13: D'Andrea L, Pérez-Rodríguez FJ, Costafreda MI, Beguiristain N, Fuentes C, Aymerich T, Guix S, Bosch A, Pintó RM. Molecular basis of the behavior of hepatitis a virus exposed to high hydrostatic pressure. Appl Environ Microbiol. 2014 Oct;80(20):6499-505. doi: 10.1128/AEM.01693-14. Epub 2014 Aug 8. PubMed PMID: 25107980; PubMed Central PMCID: PMC4178634. 14: Kalra PR, García-Moll X, Zamorano J, Kalra PA, Fox KM, Ford I, Ferrari R, Tardif JC, Tendera M, Greenlaw N, Steg PG; CLARIFY Investigators.. Impact of chronic kidney disease on use of evidence-based therapy in stable coronary artery disease: a prospective analysis of 22,272 patients. PLoS One. 2014 Jul 22;9(7):e102335. doi: 10.1371/journal.pone.0102335. eCollection 2014. PubMed PMID: 25051258; PubMed Central PMCID: PMC4106833. 15: Nagler C, Geist J, Matzke-Karasz R. Revision of the genus Tanycypris (Ostracoda, Cypricercinae) with the description of Tanycypris alfonsi n. sp., and an identification key to the genus. Zootaxa. 2014 Jun 24;3821(4):401-24. doi: 10.11646/zootaxa.3821.4.1. PubMed PMID: 24989755. 16: Coscas R, Dennery M, Javerliat I, Di Centa I, Cudennec T, Teillet L, Goëau-Brissonniere O, Coggia M. Laparoscopy versus EVAR for the treatment of abdominal aortic aneurysms in the octogenarian. Ann Vasc Surg. 2014 Oct;28(7):1634-41. doi: 10.1016/j.avsg.2014.04.018. Epub 2014 Jun 6. PubMed PMID: 24911811. 17: Zhang L, Centa T, Buck M. Structure and dynamics analysis on plexin-B1 Rho GTPase binding domain as a monomer and dimer. J Phys Chem B. 2014 Jul 3;118(26):7302-11. doi: 10.1021/jp503668k. Epub 2014 Jun 25. PubMed PMID: 24901636; PubMed Central PMCID: PMC4096216. 18: Wuliya M, Sleilaty G, Di Centa I, Khelil N, Berrebi A, Czitrom D, Mankoubi L, Noghin M, Malergue MC, Chatellier G, Debauchez M, Lansac E. An expansible aortic ring to preserve aortic root dynamics after aortic valve repair. Eur J Cardiothorac Surg. 2015 Mar;47(3):482-90; discussion 490. doi: 10.1093/ejcts/ezu174. Epub 2014 Apr 21. PubMed PMID: 24755102. 19: Delise P, Sitta N, Lanari E, Berton G, Centa M, Allocca G, Cati A, Biffi A. Long-term effect of continuing sports activity in competitive athletes with frequent ventricular premature complexes and apparently normal heart. Am J Cardiol. 2013 Nov 1;112(9):1396-402. doi: 10.1016/j.amjcard.2013.06.032. PubMed PMID: 24135302. 20: Lansac E, Di Centa I, Vojacek J, Nijs J, Hlubocky J, Mecozzi G, Debauchez M. Valve sparing root replacement: the remodeling technique with external ring annuloplasty. Ann Cardiothorac Surg. 2013 Jan;2(1):117-23. doi: 10.3978/j.issn.2225-319X.2013.01.15. PubMed PMID: 23977568; PubMed Central PMCID: PMC3741820.