Dimethylaminopropyl lauramide | CAS#3179-80-4 | skin sensitizer

MedKoo Cat#: 598751 | Name: Dimethylaminopropyl lauramide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimethylaminopropyl lauramide is a skin sensitizer.

Chemical Structure

Dimethylaminopropyl lauramide

CAS#3179-80-4

Theoretical Analysis

MedKoo Cat#: 598751

Name: Dimethylaminopropyl lauramide

CAS#: 3179-80-4

Chemical Formula: C17H36N2O

Exact Mass: 284.2828

Molecular Weight: 284.49

Elemental Analysis: C, 71.77; H, 12.76; N, 9.85; O, 5.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Dimethylaminopropyl lauramide; NSC 7989; NSC-7989; NSC7989; Lexamine L 13; Mackine 801;

IUPAC/Chemical Name

N-(3-(dimethylamino)propyl)dodecanamide

InChi Key

TWMFGCHRALXDAR-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H36N2O/c1-4-5-6-7-8-9-10-11-12-14-17(20)18-15-13-16-19(2)3/h4-16H2,1-3H3,(H,18,20)

SMILES Code

CCCCCCCCCCCC(NCCCN(C)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Dimethylaminopropyl lauramide is a skin sensitizer.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 284.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Ahmad Z, Shepherd JH, Shepherd DV, Ghose S, Kew SJ, Cameron RE, Best SM, Brooks RA, Wardale J, Rushton N. Effect of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide concentrations on the mechanical and biological characteristics of cross-linked collagen fibres for tendon repair. Regen Biomater. 2015 Jun;2(2):77-85. doi: 10.1093/rb/rbv005. Epub 2015 May 16. PubMed PMID: 26816633; PubMed Central PMCID: PMC4669024. 2: Thoreson AR, Hiwatari R, An KN, Amadio PC, Zhao C. The Effect of 1-Ethyl-3-(3-Dimethylaminopropyl) Carbodiimide Suture Coating on Tendon Repair Strength and Cell Viability in a Canine Model. J Hand Surg Am. 2015 Oct;40(10):1986-91. doi: 10.1016/j.jhsa.2015.06.117. Epub 2015 Aug 22. PubMed PMID: 26304735; PubMed Central PMCID: PMC4584204. 3: Park JY, Jung IH, Kim YK, Lim HC, Lee JS, Jung UW, Choi SH. Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects. Biomater Res. 2015 Jul 30;19:15. doi: 10.1186/s40824-015-0038-y. eCollection 2015. PubMed PMID: 26331084; PubMed Central PMCID: PMC4552459. 4: Liu S, Xu H, Yu J, Li D, Li M, Qiao X, Qin X, Yan H. Novel imidazolium-embedded N,N-dimethylaminopropyl-functionalized silica-based stationary phase for hydrophilic interaction/reversed-phase mixed-mode chromatography. Anal Bioanal Chem. 2015 Dec;407(30):8989-97. doi: 10.1007/s00216-015-9064-9. Epub 2015 Oct 1. PubMed PMID: 26427503. 5: Krishnamoorthy G, Sehgal PK, Mandal AB, Sadulla S. Development of D-lysine-assisted 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide/N-hydroxysuccinimide-initiated cross linking of collagen matrix for design of scaffold. J Biomed Mater Res A. 2013 Apr;101(4):1173-83. doi: 10.1002/jbm.a.34411. Epub 2012 Oct 23. PubMed PMID: 23090865. 6: Mahato M, Sharma AK, Kumar P. Synthesis and characterization of N-ethyl-N'-(3-dimethylaminopropyl)-guanidinyl-polyethylenimine polymers and investigation of their capability to deliver DNA and siRNA in mammalian cells. Colloids Surf B Biointerfaces. 2013 Sep 1;109:197-203. doi: 10.1016/j.colsurfb.2013.03.052. Epub 2013 Apr 9. PubMed PMID: 23643916. 7: Vashist SK. Comparison of 1-Ethyl-3-(3-Dimethylaminopropyl) Carbodiimide Based Strategies to Crosslink Antibodies on Amine-Functionalized Platforms for Immunodiagnostic Applications. Diagnostics (Basel). 2012 Aug 27;2(3):23-33. doi: 10.3390/diagnostics2030023. PubMed PMID: 26859395; PubMed Central PMCID: PMC4665462. 8: Zhou Q, Jian XD, Zhang W. [Six cases of occupational acute 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 May;29(5):348. Chinese. PubMed PMID: 21972529. 9: Sunitha K, Hemshekhar M, Gaonkar SL, Sebastin Santhosh M, Suresh Kumar M, Basappa, Priya BS, Kemparaju K, Rangappa KS, Nanjunda Swamy S, Girish KS. Neutralization of haemorrhagic activity of viper venoms by 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-car bonitrile. Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):292-9. doi: 10.1111/j.1742-7843.2011.00725.x. Epub 2011 Jun 27. PubMed PMID: 21729242. 10: Abdo K. NTP toxicity studies of dimethylaminopropyl chloride, hydrochloride (CAS No. 5407-04-5) administered by Gavage to F344/N rats and B6C3F1 mice. Toxic Rep Ser. 2007 Jul;(75):1-F8. PubMed PMID: 17703240. 11: Muskotál A, Kokol V. CE detection of N-(3-dimethylaminopropyl)-N-carbodiimide/N-hydroxysuccinimide-coupled proteins after homo- and hetero-crosslinking reactions. Electrophoresis. 2010 Mar;31(6):1097-100. doi: 10.1002/elps.200900525. PubMed PMID: 20166141. 12: Hafemann B, Ghofrani K, Gattner HG, Stieve H, Pallua N. Cross-linking by 1-ethyl-3- (3-dimethylaminopropyl)-carbodiimide (EDC) of a collagen/elastin membrane meant to be used as a dermal substitute: effects on physical, biochemical and biological features in vitro. J Mater Sci Mater Med. 2001 May;12(5):437-46. PubMed PMID: 15348284. 13: Perfetti RB, Anderson CD, Hall PL. The chemical modification of papain with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. Biochemistry. 1976 Apr 20;15(8):1735-43. PubMed PMID: 1268194. 14: Seno K, Matumura K, Oshima M, Motomizu S. Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis. Anal Sci. 2008 Apr;24(4):505-8. PubMed PMID: 18403843. 15: Lei QP, Lamb DH, Shannon AG, Cai X, Heller RK, Huang M, Zablackis E, Ryall R, Cash P. Quantification of residual EDU (N-ethyl-N'-(dimethylaminopropyl) carbodiimide (EDC) hydrolyzed urea derivative) and other residual by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Dec 25;813(1-2):103-12. PubMed PMID: 15556522. 16: Moshnikova AB, Afanasyev VN, Proussakova OV, Chernyshov S, Gogvadze V, Beletsky IP. Cytotoxic activity of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide is underlain by DNA interchain cross-linking. Cell Mol Life Sci. 2006 Jan;63(2):229-34. PubMed PMID: 16389457. 17: Kumar R, Shukla AK, Bagga E, Kumari S, Bajpai RP, Bharadwaj LM. 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide interference with Lowry method. Anal Biochem. 2005 Jan 1;336(1):132-4. PubMed PMID: 15582568. 18: Gannon WF. cis-1-(3-dimethylaminopropyl)-2,3-pentamethylenetetrahydroquinoline. J Med Chem. 1967 Mar;10(2):289. PubMed PMID: 6034088. 19: Kobayashi M, Ichishima E. Use of water-soluble 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide for the fluorescent determination of uronic acids and carboxylic acids. Anal Biochem. 1990 Aug 15;189(1):122-5. PubMed PMID: 2278381. 20: Populaire P, Decouvelaere B, Lebreton G, Pascal S, Terlain B. [Resorption, excretion and biotransformation of 3-dimethylsulfamido-10-(2-dimethylaminopropyl)-phenothiazine (Dimetotiazine) in the rabbit and dog]. Therapie. 1967 Sep-Oct;22(5):1173-89. French. PubMed PMID: 5583624.