SB 243213 dihydrochloride is a selective 5-HT2C inverse agonist (pKb = 9.8). It displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes.
MedKoo Cat#: 532656
Name: SB 243213 Dihydrochloride
CAS#: 200940-23-4 (HCl)
Chemical Formula: C22H21Cl2F3N4O2
Exact Mass:
Molecular Weight: 501.33
Elemental Analysis: C, 52.71; H, 4.22; Cl, 14.14; F, 11.37; N, 11.18; O, 6.38
The following data is based on the product molecular weight 501.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
