SB236057 is a potent and selective inverse agonist for the serotonin receptor 5-HT, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in serotonin levels in the brain, and was originally researched as a potential antidepressant. SB-236,057 also acts as a potent teratogen, producing severe musculoskeletal birth defects when rodents were exposed to it during pregnancy.
MedKoo Cat#: 532655
Name: SB236057
CAS#: 180083-49-2
Chemical Formula: C33H34N4O3
Exact Mass: 534.2631
Molecular Weight: 534.66
Elemental Analysis: C, 74.13; H, 6.41; N, 10.48; O, 8.98
The following data is based on the product molecular weight 534.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
2354.jpg "Sulfo-Cyanine3 NHS ester (potassium)")
