A-796260 or A-796,260, also known as LTI-258, is a drug developed by Abbott Laboratories that acts as a potent and selective cannabinoid CB2 receptor agonist. A-796,260 was found to be a highly selective CB2 agonist with little affinity for CB1, having a CB2 Ki of 4.6 nM vs 945 nM at CB1. It has potent analgesic and anti-inflammatory actions in animal models, being especially effective in models of neuropathic pain, but without producing cannabis-like behavioral effects.
MedKoo Cat#: 530624
Name: A-796260
CAS#: 895155-26-7
Chemical Formula: C22H30N2O2
Exact Mass: 354.2307
Molecular Weight: 354.49
Elemental Analysis: C, 74.54; H, 8.53; N, 7.90; O, 9.03
The following data is based on the product molecular weight 354.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
