MedKoo Cat#: 532275 | Name: MRS1191
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MRS1191 is a selective A3 adenosine receptor antagonist.

Chemical Structure

MRS1191
MRS1191
CAS#185222-90-6

Theoretical Analysis

MedKoo Cat#: 532275

Name: MRS1191

CAS#: 185222-90-6

Chemical Formula: C31H27NO4

Exact Mass: 477.1940

Molecular Weight: 477.56

Elemental Analysis: C, 77.97; H, 5.70; N, 2.93; O, 13.40

Price and Availability

Size Price Availability Quantity
2mg USD 530.00
5mg USD 1,100.00
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Related CAS #
No Data
Synonym
MRS1191; MRS 1191; MRS-1191.
IUPAC/Chemical Name
O3-ethyl O5-(phenylmethyl) 2-methyl-6-phenyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key
SNVFDPHQAOXWJZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H27NO4/c1-3-35-30(33)27-22(2)32-29(25-17-11-6-12-18-25)28(26(27)20-19-23-13-7-4-8-14-23)31(34)36-21-24-15-9-5-10-16-24/h4-18,26,32H,3,21H2,1-2H3
SMILES Code
O=C(C1=C(C)NC(C2=CC=CC=C2)=C(C(OCC3=CC=CC=C3)=O)C1C#CC4=CC=CC=C4)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 477.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nagaya H, Gotoh A, Kanno T, Nishizaki T. A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression. J Urol. 2013 Jan;189(1):321-8. doi: 10.1016/j.juro.2012.08.193. PubMed PMID: 23174235. 2: Kanno T, Gotoh A, Fujita Y, Nakano T, Nishizaki T. A(3) adenosine receptor mediates apoptosis in 5637 human bladder cancer cells by G(q) protein/PKC-dependent AIF upregulation. Cell Physiol Biochem. 2012;30(5):1159-68. doi: 10.1159/000343306. PubMed PMID: 23171836. 3: Kim TH, Kim YK, Woo JS. The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells. Neurochem Res. 2012 Dec;37(12):2667-77. doi: 10.1007/s11064-012-0855-5. PubMed PMID: 22878643.