MK-8133 is an orexin-2 selective receptor antagonist with favorable development properties. Antagonism of orexin receptors has shown clinical efficacy as a novel paradigm for the treatment of insomnia and related disorders.
MedKoo Cat#: 530526
Name: MK-8133
CAS#: 1431472-56-8
Chemical Formula: C23H21N5O2
Exact Mass: 399.1695
Molecular Weight: 399.45
Elemental Analysis: C, 69.16; H, 5.30; N, 17.53; O, 8.01
The following data is based on the product molecular weight 399.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |