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MedKoo Cat#: 574501 | Name: CL-387785

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CL-387785 is an irreversible and selective EGFR inhibitor with potential therapeutic activity against various type of cancer.

Chemical Structure

CL-387785
CL-387785
CAS#194423-06-6

Theoretical Analysis

MedKoo Cat#: 574501

Name: CL-387785

CAS#: 194423-06-6

Chemical Formula: C18H13BrN4O

Exact Mass: 380.0273

Molecular Weight: 381.23

Elemental Analysis: C, 56.71; H, 3.44; Br, 20.96; N, 14.70; O, 4.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CL-387785; EKB 785; EKI 785; WAY-EKI 785
IUPAC/Chemical Name
N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)but-2-ynamide
InChi Key
BTYYWOYVBXILOJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)
SMILES Code
CC#CC(NC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL