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MedKoo Cat#: 532094 | Name: L-796449 sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L-796449 is a PPAR-gamma agonist.

Chemical Structure

L-796449 sodium
L-796449 sodium
CAS#L-796449 sodium

Theoretical Analysis

MedKoo Cat#: 532094

Name: L-796449 sodium

CAS#: L-796449 sodium

Chemical Formula: C28H26ClNaO4S

Exact Mass: 494.1319

Molecular Weight: 517.01

Elemental Analysis: C, 65.05; H, 5.07; Cl, 6.86; Na, 4.45; O, 12.38; S, 6.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
194608-80-5 (free acid) L-796449 sodium
Synonym
L-796449; L 796449; L796449.
IUPAC/Chemical Name
sodium 2-[3-chloro-4-[3-[(3-phenyl-7-propyl-1-benzofuran-6-yl)oxy]propylsulfanyl]phenyl]acetate
InChi Key
DFGIWDSZLMUKGS-UHFFFAOYSA-M
InChi Code
InChI=1S/C28H27ClO4S.Na/c1-2-7-22-25(12-11-21-23(18-33-28(21)22)20-8-4-3-5-9-20)32-14-6-15-34-26-13-10-19(16-24(26)29)17-27(30)31;/h3-5,8-13,16,18H,2,6-7,14-15,17H2,1H3,(H,30,31);/q;+1/p-1
SMILES Code
O=C([O-])CC1=CC=C(SCCCOC2=C(CCC)C3=C(C=C2)C(C4=CC=CC=C4)=CO3)C(Cl)=C1.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 517.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pereira MP, Hurtado O, Cárdenas A, Alonso-Escolano D, Boscá L, Vivancos J, Nombela F, Leza JC, Lorenzo P, Lizasoain I, Moro MA. The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. J Neuropathol Exp Neurol. 2005 Sep;64(9):797-805. PubMed PMID: 16141790. 2: Castrillo A, Mojena M, Hortelano S, Boscá L. Peroxisome proliferator-activated receptor-gamma-independent inhibition of macrophage activation by the non-thiazolidinedione agonist L-796,449. Comparison with the effects of 15-deoxy-delta(12,14)-prostaglandin J(2). J Biol Chem. 2001 Sep 7;276(36):34082-8. PubMed PMID: 11438523.