GPP78, also known as CAY10618, is a NMPRTase Inhibitor. The inhibition of NAD synthesis or salvage pathways has been proposed as a novel target for antitumoral drugs. GPP78 displays an IC(50) for cytotoxicity in vitro of 3.8 +/- 0.3 nM and an IC(50) for NAD depletion of 3.0 +/- 0.4 nM.
MedKoo Cat#: 407399
Name: GPP78
CAS#: 1202580-59-3
Chemical Formula: C27H29N5O
Exact Mass: 439.2372
Molecular Weight: 439.56
Elemental Analysis: C, 73.78; H, 6.65; N, 15.93; O, 3.64
The following data is based on the product molecular weight 439.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
