MedKoo Cat#: 527725 | Name: JNJ-38877618
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ-38877618 is a hepatocyte growth factor receptor (HGFR; MET; c-Met) inhibitor potentially for the treatment of solid tumours.

Chemical Structure

JNJ-38877618
JNJ-38877618
CAS#943540-74-7

Theoretical Analysis

MedKoo Cat#: 527725

Name: JNJ-38877618

CAS#: 943540-74-7

Chemical Formula: C20H12F2N6

Exact Mass: 374.1092

Molecular Weight: 374.35

Elemental Analysis: C, 64.17; H, 3.23; F, 10.15; N, 22.45

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
JNJ-38877618; JNJ 38877618; JNJ38877618
IUPAC/Chemical Name
6-(difluoro(6-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
InChi Key
KOAWAWHSMVKCON-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H
SMILES Code
FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 374.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL