MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 531754 | Name: CV-1674

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CV-1674 induces selective coronary vasodilation with less depression on cardiohemodynamics.

Chemical Structure

CV-1674
CV-1674
CAS#37151-17-0

Theoretical Analysis

MedKoo Cat#: 531754

Name: CV-1674

CAS#: 37151-17-0

Chemical Formula: C17H19N5O5

Exact Mass: 373.1386

Molecular Weight: 373.37

Elemental Analysis: C, 54.69; H, 5.13; N, 18.76; O, 21.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
CV-1674; CV 1674; CV1674; NSC 310669.
IUPAC/Chemical Name
(2R,3R,4S,5R)-2-(6-amino-2-(4-methoxyphenyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChi Key
VKSRAKNPXOTFAX-CNEMSGBDSA-N
InChi Code
InChI=1S/C17H19N5O5/c1-26-9-4-2-8(3-5-9)15-20-14(18)11-16(21-15)22(7-19-11)17-13(25)12(24)10(6-23)27-17/h2-5,7,10,12-13,17,23-25H,6H2,1H3,(H2,18,20,21)/t10-,12-,13-,17-/m1/s1
SMILES Code
O[C@H]1[C@H](N2C=NC3=C(N)N=C(C4=CC=C(OC)C=C4)N=C23)O[C@H](CO)[C@H]1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 373.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hirata M, Kawazoe K, Tanabe M, Kikuchi K. Effects of a 2-substituted adenosine derivative, 2-(p-methoxyphenyl)-adenosine (CV-1674) on coronary and cardiohemodynamics, and myocardial energetics. Jpn J Pharmacol. 1977 Oct;27(5):689-700. PubMed PMID: 592558. 2: Singh YN, Dryden WF, Chen H. The inhibitory effects of some adenosine analogues on transmitter release at the mammalian neuromuscular junction. Can J Physiol Pharmacol. 1986 Nov;64(11):1446-50. PubMed PMID: 3024786. 3: Paton DM. Presynaptic inhibition of neurotransmission in rat vas deferens by 2-(p-methoxyphenyl) adenosine, ethyl adenosine-5'-carboxylate and N-cyclopropyl adenosine-5'-carboxamide. J Pharm Pharmacol. 1980 Feb;32(2):133-5. PubMed PMID: 6103035. 4: van der Ploeg I, Ahlberg S, Parkinson FE, Olsson RA, Fredholm BB. Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn Schmiedebergs Arch Pharmacol. 1996 Feb;353(3):250-60. PubMed PMID: 8692279.

View History

Lamivudine, (+/-)-trans-

Lamivudine, (+/-)-trans-