MedKoo Cat#: 513699 | Name: CL82198 free base
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CL82198 is a MMP13 inhibitor which is a target for pharmacologic treatment for preventing osteoarthritis progression.

Chemical Structure

CL82198 free base
CL82198 free base
CAS#307002-71-7 (free base)

Theoretical Analysis

MedKoo Cat#: 513699

Name: CL82198 free base

CAS#: 307002-71-7 (free base)

Chemical Formula: C17H22N2O3

Exact Mass: 302.1630

Molecular Weight: 302.37

Elemental Analysis: C, 67.53; H, 7.33; N, 9.26; O, 15.87

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 700.00 2 Weeks
50mg USD 1,050.00 2 Weeks
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Synonym
CL82198; CL 82198; CL-82198.
IUPAC/Chemical Name
N-[4-(morpholin-4-yl)butyl]-1-benzofuran-2-carboxamide
InChi Key
KUJQEQAVMNFFAO-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H22N2O3/c20-17(16-13-14-5-1-2-6-15(14)22-16)18-7-3-4-8-19-9-11-21-12-10-19/h1-2,5-6,13H,3-4,7-12H2,(H,18,20)
SMILES Code
O=C(C(O1)=CC2=C1C=CC=C2)NCCCCN3CCOCC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 302.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang M, Sampson ER, Jin H, Li J, Ke QH, Im HJ, Chen D. MMP13 is a critical target gene during the progression of osteoarthritis. Arthritis Res Ther. 2013 Jan 8;15(1):R5. doi: 10.1186/ar4133. PubMed PMID: 23298463; PubMed Central PMCID: PMC3672752.