MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 513684 | Name: CGS-12066 maleate salt

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CGS-12066 maleate salt is a 5-HT1B serotonin receptor agonist.

Chemical Structure

CGS-12066 maleate salt
CGS-12066 maleate salt
CAS#1350965-83-1 (maleate)

Theoretical Analysis

MedKoo Cat#: 513684

Name: CGS-12066 maleate salt

CAS#: 1350965-83-1 (maleate)

Chemical Formula: C21H21F3N4O4

Exact Mass:

Molecular Weight: 450.42

Elemental Analysis: C, 56.00; H, 4.70; F, 12.65; N, 12.44; O, 14.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
1350965-83-1 (maleate) 109028-09-3 (free base)
Synonym
CGS-12066 maleate salt; CGS-12066; CGS -12066; CGS12066 .
IUPAC/Chemical Name
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt
InChi Key
ZBPAHEUAJMCLRD-BTJKTKAUSA-N
InChi Code
InChI=1S/C17H17F3N4.C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES Code
CN1CCN(C2=NC3=C(N4C2=CC=C4)C=CC(C(F)(F)F)=C3)CC1.O=C(O)/C=C\C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 450.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: García-Pedraza JÁ, García M, Martín ML, Morán A. 5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats. Vascul Pharmacol. 2015 Sep;72:172-80. doi: 10.1016/j.vph.2015.05.003. PubMed PMID: 26003124. 2: García-Pedraza JA, García M, Martín ML, Rodríguez-Barbero A, Morán A. 5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature. Vascul Pharmacol. 2016 Apr;79:51-9. doi: 10.1016/j.vph.2015.11.039. PubMed PMID: 26586311. 3: García-Pedraza JÁ, García M, Martín ML, Morán A. Pharmacological evidence that 5-HT1D activation induces renal vasodilation by NO pathway in rats. Clin Exp Pharmacol Physiol. 2015 Jun;42(6):640-7. doi: 10.1111/1440-1681.12397. PubMed PMID: 25854421.