BVT173187 |CAS#1374984-75-4 | FPR1 inhibitor

MedKoo Cat#: 531645 | Name: BVT173187

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor. BVT173187 may be a therapeutic target for the development of novel drugs that may be used to reduce injuries in inflammatory diseases including asthma, rheumatoid arthritis, Alzheimer's disease and cardiovascular diseases.

Chemical Structure

BVT173187

CAS#1374984-75-4

Theoretical Analysis

MedKoo Cat#: 531645

Name: BVT173187

CAS#: 1374984-75-4

Chemical Formula: C14H10Cl3NO2

Exact Mass: 328.9777

Molecular Weight: 330.59

Elemental Analysis: C, 50.86; H, 3.05; Cl, 32.17; N, 4.24; O, 9.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

BVT173187; BVT 173187; BVT-173187.

IUPAC/Chemical Name

3,5-dichloro-N-(2-chloro-5-methylphenyl)-2-hydroxybenzamide

InChi Key

UCOQCHLODZCXRH-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H10Cl3NO2/c1-7-2-3-10(16)12(4-7)18-14(20)9-5-8(15)6-11(17)13(9)19/h2-6,19H,1H3,(H,18,20)

SMILES Code

O=C(NC1=CC(C)=CC=C1Cl)C2=CC(Cl)=CC(Cl)=C2O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 330.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Cevik-Aras H, Kalderén C, Jenmalm Jensen A, Oprea T, Dahlgren C, Forsman H. A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1. Biochem Pharmacol. 2012 Jun 15;83(12):1655-62. doi: 10.1016/j.bcp.2012.02.024. PubMed PMID: 22410002.