MedKoo Cat#: 530142 | Name: REC-2615 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

REC-2615 HCl is a α1B-adrenoceptor antagonist potentially for the treatment of female sexual dysfunction.

Chemical Structure

REC-2615 HCl
REC-2615 HCl
CAS#173059-17-1

Theoretical Analysis

MedKoo Cat#: 530142

Name: REC-2615 HCl

CAS#: 173059-17-1

Chemical Formula: C26H34ClN5O5

Exact Mass: 0.0000

Molecular Weight: 532.04

Elemental Analysis: C, 58.70; H, 6.44; Cl, 6.66; N, 13.16; O, 15.04

Price and Availability

Size Price Availability Quantity
10mg USD 450.00
50mg USD 1,050.00
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Related CAS #
No Data
Synonym
REC-2615; Rec-15; 2615; REC2615; Rec15; REC 2615; Rec 15
IUPAC/Chemical Name
1-(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)-2-(2-isopropyl-6-methoxyphenoxy)ethan-1-one hydrochloride
InChi Key
YLPWNPUPMQZIKN-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H33N5O5.ClH/c1-16(2)17-7-6-8-20(33-3)24(17)36-15-23(32)30-9-11-31(12-10-30)26-28-19-14-22(35-5)21(34-4)13-18(19)25(27)29-26;/h6-8,13-14,16H,9-12,15H2,1-5H3,(H2,27,28,29);1H
SMILES Code
O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)COC4=C(OC)C=CC=C4C(C)C.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# 173059-17-1(REC-2615 hydrochloride) 173059-47-7(REC-2615 Free base)

Preparing Stock Solutions

The following data is based on the product molecular weight 532.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: da Silva ES, Flores RA, Cella EC, Levone BR, Taschetto AP, Kochenborger L, Terenzi MG, Faria MS, Paschoalini MA. Blockade of median raphe nucleus α1-adrenoceptor subtypes increases food intake in rats. Pharmacol Biochem Behav. 2014 Sep;124:350-5. doi: 10.1016/j.pbb.2014.06.010. PubMed PMID: 24955865. 2: Sironi G, Colombo D, Poggesi E, Leonardi A, Testa R, Rampin O, Bernabé J, Giuliano F. Effects of intracavernous administration of selective antagonists of alpha(1)-adrenoceptor subtypes on erection in anesthetized rats and dogs. J Pharmacol Exp Ther. 2000 Mar;292(3):974-81. PubMed PMID: 10688612. 3: Kim NN, Min K, Huang YH, Goldstein I, Traish AM. Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina. Life Sci. 2002 Nov 1;71(24):2909-20. PubMed PMID: 12377271. 4: Bayés M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2007 Nov;29(9):625-55. PubMed PMID: 18193114. 5: Brown, A. D., Blagg, J., & Reynolds, D. S. (2007). Designing drugs for the treatment of female sexual dysfunction. Drug discovery today, 12(17-18), 757-766.