Cipralisant, also known as GT-2331, is a potent Histamine H3 receptor ligand. The drug exhibits complex pharmacology: it behaves as an antagonist in a guinea pig jejunum contraction assay and mouse disogenia model, as a partial agonist in a rat brain synaptosome model, and as a full agonist at recombinant H3 receptors. In preclinical models, cipralisant enhanced wakefulness and improved learning in developmental rat models.
MedKoo Cat#: 530130
Name: Cipralisant maleate
CAS#: 223420-20-0 (maleate)
Chemical Formula: C18H24N2O4
Exact Mass: 216.1600
Molecular Weight: 332.40
Elemental Analysis: C, 65.04; H, 7.28; N, 8.43; O, 19.25
The following data is based on the product molecular weight 332.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
