Foslinanib, also known as TRX-818, CVM-1118, is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated, TRX-818, upon oral administration appears to induce cancer cell apoptosis and inhibits cancer cell proliferation. This agent also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.
MedKoo Cat#: 206766
Name: Foslinanib sodium
CAS#: 1256037-62-3 (sodium)
Chemical Formula: C16H11FNNa2O5P
Exact Mass: 0.0000
Molecular Weight: 393.22
Elemental Analysis: C, 48.87; H, 2.82; F, 4.83; N, 3.56; Na, 11.69; O, 20.34; P, 7.88
The following data is based on the product molecular weight 393.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
