NSC61610 | CAS#500538-94-3 | LANCL2 ligand

MedKoo Cat#: 530323 | Name: NSC61610

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC61610 is a LANCL2 ligand. NSC61610 showed anti-inflammatory activity and potential useful for inflammatory bowel disease and influenza-driven inflammation . LANCL2 is a novel therapeutic target for the discovery and development of new classes of orally active drugs against chronic metabolic, immune-mediated and infectious diseases.

Chemical Structure

NSC61610

CAS#500538-94-3

Theoretical Analysis

MedKoo Cat#: 530323

Name: NSC61610

CAS#: 500538-94-3

Chemical Formula: C34H24N6O2

Exact Mass: 548.1961

Molecular Weight: 548.61

Elemental Analysis: C, 74.44; H, 4.41; N, 15.32; O, 5.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

NSC61610; NSC-61610; NSC 61610; MLS000766212; SMR000528839.

IUPAC/Chemical Name

N1,N4-bis(3-(1H-benzo[d]imidazol-2-yl)phenyl)terephthalamide

InChi Key

WSXIJTIFOWCMIQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C34H24N6O2/c41-33(35-25-9-5-7-23(19-25)31-37-27-11-1-2-12-28(27)38-31)21-15-17-22(18-16-21)34(42)36-26-10-6-8-24(20-26)32-39-29-13-3-4-14-30(29)40-32/h1-20H,(H,35,41)(H,36,42)(H,37,38)(H,39,40)

SMILES Code

C1=CC=C2C(=C1)NC(=N2)C3=CC(=CC=C3)NC(=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC(=C5)C6=NC7=CC=CC=C7N6

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 548.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Zhang Q, He Q, Xue F, Ma J. Inhibitor screening of lactate dehydrogenase C4 from black-lipped pika in the Western Sichuan Plateau. Biosci Biotechnol Biochem. 2014;78(4):651-4. doi: 10.1080/09168451.2014.890038. PubMed PMID: 25036963. 2: Lu P, Hontecillas R, Philipson CW, Bassaganya-Riera J. Lanthionine synthetase component C-like protein 2: a new drug target for inflammatory diseases and diabetes. Curr Drug Targets. 2014 Jun;15(6):565-72. Review. PubMed PMID: 24628287. 3: Lu P, Hontecillas R, Horne WT, Carbo A, Viladomiu M, Pedragosa M, Bevan DR, Lewis SN, Bassaganya-Riera J. Computational modeling-based discovery of novel classes of anti-inflammatory drugs that target lanthionine synthetase C-like protein 2. PLoS One. 2012;7(4):e34643. doi: 10.1371/journal.pone.0034643. PubMed PMID: 22509338; PubMed Central PMCID: PMC3324509.