Org-13011 fumarate | CAS#142494-12-0 | 142494-13-1 | 5-HT1A receptor agonist

MedKoo Cat#: 530310 | Name: Org-13011 fumarate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Org-13011 fumarate is a 5-HT1A receptor agonist.

Chemical Structure

Org-13011 fumarate

CAS#142494-13-1 (fumarate)

Theoretical Analysis

MedKoo Cat#: 530310

Name: Org-13011 fumarate

CAS#: 142494-13-1 (fumarate)

Chemical Formula: C22H29F3N4O5

Exact Mass:

Molecular Weight: 486.49

Elemental Analysis: C, 54.32; H, 6.01; F, 11.72; N, 11.52; O, 16.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Org-13011 fumarate; Org 13011; Org13011.

IUPAC/Chemical Name

2-Pyrrolidinone, 1-(4-(4-(4-(trifluoromethyl)-2-pyridinyl)-1-piperazinyl)butyl)-, (E)-2-butenedioate

InChi Key

KILJTUTVUORPFQ-WLHGVMLRSA-N

InChi Code

InChI=1S/C18H25F3N4O.C4H4O4/c19-18(20,21)15-5-6-22-16(14-15)24-12-10-23(11-13-24)7-1-2-8-25-9-3-4-17(25)26;5-3(6)1-2-4(7)8/h5-6,14H,1-4,7-13H2;1-2H,(H,5,6)(H,7,8)/b;2-1+

SMILES Code

O=C1N(CCCCN2CCN(C3=NC=CC(C(F)(F)F)=C3)CC2)CCC1.O=C(O)/C=C/C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Related CAS# 142494-12-0 (Org-13011 free base) 142494-13-1 (Org-13011 fumarate)

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 486.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: van Hoof P, Lammers R, v Puijenbroek R, v d Schans M, Carlier P, Kellenbach E. Polymorphism of the CNS active drug Org 13011: the application of high temperature analysis to detect new polymorphs. Int J Pharm. 2002 May 15;238(1-2):215-28. PubMed PMID: 11996825. 2: Berendsen HH, Broekkamp CL. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. Eur Neuropsychopharmacol. 1999 Jun;9(4):345-9. PubMed PMID: 10422896.