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MedKoo Cat#: 526988 | Name: GW-597901

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GW-597901, also known as GSK-597901; GW-597901X, is an β2 adrenergic receptor agonist potentially for the treatment of asthma and chronic obstructive.

Chemical Structure

GW-597901
GW-597901
CAS#452339-68-3

Theoretical Analysis

MedKoo Cat#: 526988

Name: GW-597901

CAS#: 452339-68-3

Chemical Formula: C25H38N2O6S

Exact Mass: 494.2451

Molecular Weight: 494.65

Elemental Analysis: C, 60.70; H, 7.74; N, 5.66; O, 19.41; S, 6.48

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
GW-597901; GW 597901; GW597901; GW-597901X; GSK-597901; GSK 597901; GSK597901.
IUPAC/Chemical Name
(R)-3-(4-((6-((2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide
InChi Key
GBTODAKMABNGIJ-VWLOTQADSA-N
InChi Code
InChI=1S/C25H38N2O6S/c26-34(31,32)23-10-7-9-20(16-23)8-3-6-15-33-14-5-2-1-4-13-27-18-25(30)21-11-12-24(29)22(17-21)19-28/h7,9-12,16-17,25,27-30H,1-6,8,13-15,18-19H2,(H2,26,31,32)/t25-/m0/s1
SMILES Code
O=S(C1=CC=CC(CCCCOCCCCCCNC[C@H](O)C2=CC=C(O)C(CO)=C2)=C1)(N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 494.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gnadt M, Trammer B, Kardziev B, Bayliss MK, Edwards CD, Schmidt M, Högger P. Comparison of the bronchodilating effects of inhaled β₂-agonists after methacholine challenge in a human lung reperfusion model. Eur J Pharm Biopharm. 2012 Aug;81(3):617-26. doi: 10.1016/j.ejpb.2012.04.013. PubMed PMID: 22561952. 2: Gnadt M, Trammer B, Freiwald M, Kardziev B, Bayliss MK, Edwards CD, Schmidt M, Friedel G, Högger P. Methacholine delays pulmonary absorption of inhaled β(2)-agonists due to competition for organic cation/carnitine transporters. Pulm Pharmacol Ther. 2012 Feb;25(1):124-34. doi: 10.1016/j.pupt.2011.12.009. PubMed PMID: 22245488.