Ro 31-0313 | CAS#77273-77-9

MedKoo Cat#: 526185 | Name: Ro 31-0313

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ro 31-0313 is a metabolite of Ro 03-8799, radiation sensitizing agent.

Chemical Structure

Ro 31-0313

CAS#77273-77-9

Theoretical Analysis

MedKoo Cat#: 526185

Name: Ro 31-0313

CAS#: 77273-77-9

Chemical Formula: C11H18N4O4

Exact Mass: 270.1328

Molecular Weight: 270.29

Elemental Analysis: C, 48.88; H, 6.71; N, 20.73; O, 23.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Ro 31-0313; Ro 310313; Ro-31-0313.

IUPAC/Chemical Name

2-Nitro-alpha-piperidinomethyl-1-imidazole ethanol N-oxide

InChi Key

BZKCKUMYSBPPIC-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H18N4O4/c1-11(16,9-12-5-3-2-4-6-12)13-7-8-14(17)10(13)15(18)19/h7-8,16H,2-6,9H2,1H3

SMILES Code

CC(N1C=C[N+]([O-])=C1[N+]([O-])=O)(CN2CCCCC2)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 270.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Walton MI, Bleehen NM, Workman P. Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice. Br J Cancer. 1989 May;59(5):667-73. PubMed PMID: 2736198; PubMed Central PMCID: PMC2247237. 2: Walton MI, Bleehen NM, Workman P. The effects of whole body hyperthermia on the pharmacokinetics and toxicity of the basic 2-nitroimidazole radiosensitizer Ro 03-8799 in mice. Br J Cancer. 1987 May;55(5):469-76. PubMed PMID: 3606940; PubMed Central PMCID: PMC2001726. 3: Malcolm SL, Lee A, Groves JK. High-performance liquid chromatographic analysis of the new hypoxic cell radiosensitiser, Ro 03-8799, in biological samples. J Chromatogr. 1983 Apr 8;273(2):327-33. PubMed PMID: 6863447.