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MedKoo Cat#: 329310 | Name: Benactyzine Hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Benactyzine Hydrochloride, also known as Suavitil, is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.

Chemical Structure

Benactyzine Hydrochloride
Benactyzine Hydrochloride
CAS#57-37-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 329310

Name: Benactyzine Hydrochloride

CAS#: 57-37-4 (HCl)

Chemical Formula: C20H26ClNO3

Exact Mass: 0.0000

Molecular Weight: 363.88

Elemental Analysis: C, 66.02; H, 7.20; Cl, 9.74; N, 3.85; O, 13.19

Price and Availability

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5g USD 450.00 2 Weeks
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Related CAS #
302-40-9 (free base) 57-37-4 (HCl)
Synonym
Benactyzine Hydrochloride; EA 2092; EA-2092; EA2092; Suavitil; Phebex; Phobex; Cedad; Cevanol; Deprol; Lucidil; Morcain; Nutinal; Parasan
IUPAC/Chemical Name
2-(diethylamino)ethyl 2-hydroxy-2,2-diphenylacetate hydrochloride
InChi Key
ZCEHOOLYWQBGQO-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H25NO3.ClH/c1-3-21(4-2)15-16-24-19(22)20(23,17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,23H,3-4,15-16H2,1-2H3;1H
SMILES Code
OC(C1=CC=CC=C1)(C2=CC=CC=C2)C(OCCN(CC)CC)=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# 302-40-9 (Benactyzine) 57-37-4 (Benactyzine Hydrochloride)

Preparing Stock Solutions

The following data is based on the product molecular weight 363.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brown B, Haegerstrom-Portnoy G, Baker R, Adams AJ, Jones RT. Effects of benactyzine hydrochloride on dynamic vision functions. Aviat Space Environ Med. 1982 Nov;53(11):1123-8. PubMed PMID: 7150174. 2: Siedlanowska H, Krówczyński L. [Kinetics of decomposition of benzilic acid esters. 3. Study of kinetics of decomposition of benactyzine hydrochloride and methyliodide and diphemin hydrochloride]. Acta Pol Pharm. 1966;23(6):505-16. Polish. PubMed PMID: 5960081. 3: GLOW PH. The blocking effect of benactyzine hydrochloride on a behaviour disturbance induced with lysergic acid diethylamide. Br J Psychol. 1959 Nov;50:338-48. PubMed PMID: 13828510. 4: BATEMAN JC, CARLTON HM. Meprobamate and benactyzine hydrochloride (deprol) as adjunctive therapy for patients with advanced cancer. Antibiotic Med Clin Ther (New York). 1959 Nov;6:648-52. PubMed PMID: 13797484. 5: LAMPHIER TA. Benactyzine hydrochloride; the treatment of one hundred hospitalized patients. Conn Med. 1959 Apr;23(4):220-3. PubMed PMID: 13639572. 6: SMITH GW, UHR L, POLLARD JC, MILLER JG. An exploratory study of the behavioral effects of suavitil (benactyzine hydrochloride). Med Bull (Ann Arbor). 1958 Oct;24(10):402-7. PubMed PMID: 13603890. 7: ALEXANDER L. Chemotherapy of depression; use of meprobamate combined with benactyzine (2-diethylaminoethyl benzilate) hydrochloride. J Am Med Assoc. 1958 Mar 1;166(9):1019-23. PubMed PMID: 13502099. 8: WELSH AL, EDE M. Experience with benactyzine hydrochloride (suavitil) in dermatologic practice. AMA Arch Derm. 1957 Oct;76(4):466-70. PubMed PMID: 13457433. 9: MACLEAN RE. Benactyzine hydrochloride (suavitil) in out-patient psychiatric treatment: preliminary study. Med J Aust. 1957 Jan 19;44(3):67-70. PubMed PMID: 13399522. 10: Longrée R. [The hydroxylaminolysis kinetics of benactyzine hydrochloride (author's transl)]. J Pharm Belg. 1977 Mar-Apr;32(2):167-78. French. PubMed PMID: 894477. 11: SETTEL E. Treatment of depression in the elderly with a meprobamate-benactyzine hydrochloride combination (deprol). Antibiotic Med Clin Ther (New York). 1960 Jan;7:28-32. PubMed PMID: 14445207. 12: RUCHWARGER A. Use of deprol (meprobamate combined with benactyzine hydrochloride) in the office treatment of depression. Med Ann Dist Columbia. 1959 Aug;28(8):438-41. PubMed PMID: 13673692. 13: ALEXANDER L. Meprobamate combined with 2-diethyl-aminoethyl benzilate hydrochloride (benactyzine). Dis Nerv Syst. 1958 Jul;19(7, Part 2):52-3. PubMed PMID: 13561919. 14: AYD FJ Jr. A clinical report on benactyzine hydrochloride. N Engl J Med. 1957 Oct 3;257(14):669-70. PubMed PMID: 13477367. 15: BERGER FM, HENDLEY CD, LYNES TE. Pharmacology of the psychotherapeutic drug benactyzine (beta-diethylaminoethyl benzilate hydrochloride). Proc Soc Exp Biol Med. 1956 Jul;92(3):563-6. PubMed PMID: 13359467.