Tyrphostin AG-528 | CAS#133550-49-9 | EGFR inhibitor

MedKoo Cat#: 406843 | Name: Tyrphostin AG-528

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tyrphostin AG-528, also known as Tyrphostin B66, is a EGFR protein tyrosine kinase inhibitor.

Chemical Structure

Tyrphostin AG-528

CAS#133550-49-9

Theoretical Analysis

MedKoo Cat#: 406843

Name: Tyrphostin AG-528

CAS#: 133550-49-9

Chemical Formula: C18H14N2O3

Exact Mass: 306.1004

Molecular Weight: 306.32

Elemental Analysis: C, 70.58; H, 4.61; N, 9.15; O, 15.67

Price and Availability

Size	Price	Availability
50mg	USD 250.00	2 Weeks
100mg	USD 450.00	2 Weeks
200mg	USD 650.00	2 Weeks
500mg	USD 1,450.00	2 Weeks
1g	USD 2,450.00	2 Weeks
2g	USD 4,450.00	2 Weeks

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Related CAS #

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Synonym

Tyrphostin AG-528; Tyrphostin AG 528; Tyrphostin AG528; AG 528; AG528; AG-528; Tyrphostin B-66; Tyrphostin-B66; Tyrphostin B66.

IUPAC/Chemical Name

N-(3′,4′-Dihydroxybenzylidenecyanoacetyl)indoline

InChi Key

MYKCTDWWIWGLHW-NTEUORMPSA-N

InChi Code

InChI=1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2/b14-9+

SMILES Code

O=C(N1CCC2=C1C=CC=C2)/C(C#N)=C/C3=CC=C(O)C(O)=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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