MedKoo Cat#: 526057 | Name: Proglycosyn

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Proglycosyn promotes glycogen synthesis and phosphoprotein phosphatase activity.

Chemical Structure

Proglycosyn
Proglycosyn
CAS#103793-22-2

Theoretical Analysis

MedKoo Cat#: 526057

Name: Proglycosyn

CAS#: 103793-22-2

Chemical Formula: C13H15BrN2O2

Exact Mass: 310.0317

Molecular Weight: 311.18

Elemental Analysis: C, 50.18; H, 4.86; Br, 25.68; N, 9.00; O, 10.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Proglycosyn; LY-177507; LY 177507; LY177507.
IUPAC/Chemical Name
1-Methyl-3 (2-oxo-2-(3-methoxyphenyl)ethyl)-1H-imidazolium bromide
InChi Key
LDFPYRMYXCBYSZ-UHFFFAOYSA-M
InChi Code
InChI=1S/C13H15N2O2.BrH/c1-14-6-7-15(10-14)9-13(16)11-4-3-5-12(8-11)17-2;/h3-8,10H,9H2,1-2H3;1H/q+1;/p-1
SMILES Code
COC1=CC(C(C[N+]2=CN(C)C=C2)=O)=CC=C1.[Br-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 311.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Flückiger-Isler R, Kux E, Walter P. 5-Iodotubercidin and proglycosyn: a comparison of two glycogenic compounds in hepatocytes from fasted rats. Biochim Biophys Acta. 1996 Apr 24;1311(2):77-84. PubMed PMID: 8630333. 2: Van Schaftingen E. Involvement of phosphorylase kinase inhibition in the effect of resorcinol and proglycosyn on glycogen metabolism in the liver. Eur J Biochem. 1995 Nov 15;234(1):301-7. PubMed PMID: 8529656. 3: Van Schaftingen E, de Hoffmann E. Effect of proglycosyn and other phenolic compounds on glycogen metabolism in isolated hepatocytes. Potential role of glucuronidated metabolites. Eur J Biochem. 1993 Dec 1;218(2):745-51. PubMed PMID: 8269965. 4: Guzmán M, Geelen MJ, Harris RA. Effects of proglycosyn (LY177507) on fatty acid metabolism in rat hepatocytes. Arch Biochem Biophys. 1993 Aug 15;305(1):141-6. PubMed PMID: 8102045. 5: Yamanouchi K, Stephens TW, Chikada K, Dominianni SJ, Behforouz H, Scislowski P, DePaoli-Roach A, Allmann DW, Harris RA. Metabolic effects of proglycosyn. Arch Biochem Biophys. 1992 May 1;294(2):609-15. PubMed PMID: 1314546. 6: Guo ZK, Wals PA, Katz J. Stimulation of glycogen synthesis by proglycosyn (LY177507) by isolated hepatocytes of normal and streptozotocin diabetic rats. J Biol Chem. 1991 Nov 25;266(33):22323-7. PubMed PMID: 1939254.